Autoimmune hepatitis is a chronic hepatitis that occurs in children and adults of all ages. Diagnosis is based upon characteristic serologic and histologic findings and the exclusion of other forms of chronic liver disease. Guidelines issued by the AASLD suggest the following diagnostic considerations: The diagnosis should be made in patients with compatible clinical signs, symptoms, and labora...

Patients with autoimmune urticaria show a higher rate of seropositivity for other autoantibodies and often have a history of autoimmune conditions. They also tend to have more severe symptoms and to have a poor response to conventional antihistamine treatment. Autoimmune hepatitis is a chronic inflammatory disorder in which progressive liver injury is thought to be the result of a T-cell-mediat...

Background: Ataxia telangiectasia (AT) is one of the combined immunodeficiency syndromes with immunologic, neurologic, endocrinologic, hepatic and cutaneous abnormalities. Regarding the fact that autoimmune disorders; such as autoimmune hemolytic anemia (AIHA), are not generally expected in the course of AT, we present a patient with an unusual presentation of these two conditions. Case present...

introduction systemic lupus erythematous (sle) is among rheumatic diseases of unknown etiology. fever of unknown origin (fuo) has been rarely reported to be the presenting sign of sle. presence of four or more sle criteria is diagnostic for the disease. however, presentations may occur serially which make it much more difficult to diagnose an already questioned fuo. case presentation our case o...

type i diabetes mellitus (dm) is frequently associated with autoimmune thyroid disease (atd). association of atd and type i dm has been described with varying frequencies but there is still debate about the situation in the iranian population. we investigated the prevalence of anti thyroid peroxidase (anti-tpo) antibodies and atd in children and adolescents with type i dm. a total of 145 patien...

conclusions aih in our region presents with advanced disease affecting predominantly children and adolescents. there is a genetic association of hla dr6 along with other alleles and antigens in our patients with aih. objectives the aim of this study was to evaluate the clinical profile of autoimmune hepatitis (aih), and determine the associated antigens and alleles by performing hla typing. pat...