Lipoinjection is a promising treatment, but is currently limited by unpredictable outcomes and a low rate of graft survival due to partial necrosis. To address these problems we developed a novel strategy called Cell-Assisted Lipotransfer (CAL) in which autologous adipose-derived stem (stromal) cell (ASC) supplementation is used in combination with lipoinjection. A stromal vascular fraction (SV...

BACKGROUND Autologous fat is an excellent soft tissue filler with cosmetic and reconstructive utility. However, graft longevity is unpredictable. OBJECTIVE This study sought to evaluate the effect on in vivo fat graft performance of contemporary adipocyte tissue engineering techniques that have not previously been applied to mature fat cells due to the difficulty of their purification and the...

OBJECTIVES We investigated the long-term results of autologous fat injections for unilateral vocal cord paralysis and laryngofissure and cordectomy defects. PATIENTS AND METHODS We evaluated the efficacy of autologous fat injections in 21 patients (16 males, 5 females; mean age 57 years; range 24 to 72 years) with unilateral vocal cord paralysis (n=11) and cordectomy defects (n=10) in the lig...

Cosmetic surgeons have experimented with a variety of substances to improve soft tissue deformities of the face. Autologous fat grafting provides significant advantages over other modalities because it leaves no scar, is easy to use and is well tolerated by most patients. Autologous fat grafting has become one of the most popular techniques in the field of facial plastic surgery. Unfortunately,...

OBJECTIVES To apply the technique of injection of a combination of autologous fascia lata and fat into the vocal fold via the cricothyroid gap for unilateral vocal fold paralysis and to evaluate the therapeutic effect in 12 patients who underwent the procedure. DESIGN Retrospective analysis of 12 patients. SETTING Academic research. PATIENTS A mixture of autologous fascia lata and fat was...

Purpose  This study aims to evaluate the safety and efficacy of autologous aspirated and purified fat tissue injected percutaneously into the knee joint for the treatment of symptomatic osteoarthritis (OA). Methods  We reviewed 30 patients, who received an autologous percutaneous fat injection for the treatment of knee OA, from January 2012 to March 2015. Mean patients' age was 63.3 ± 5.3 years...

Conventional breast cancer extirpation involves resection of parts of or the whole gland, resulting in asymmetry and disfiguration. Given the unsatisfactory aesthetic outcomes, patients often desire postmastectomy reconstructive procedures. Autologous fat grafting has been proposed for reconstructive purposes for decades to restore form and anatomy after mastectomy. Fat has the inherent advanta...

Objective: Autologous lipoinjection for patulous Eustachian tube dysfunction was investigated. We studied the technique of fat harvesting, fat tissue changes due to processing, clinical application and preliminary outcomes. Design: Prospective pilot cohort study. Methods: Transnasal endoscopic injection of autologous lipoinjection into the posterior cushin was performed in 8 patients as a new t...

For recent years, use of autologous fat injection has increased significantly in facial contouring surgery. Along with such increase in use, complications like atypical mycoplasma infection have been also on the increasing trend. The authors report two cases of Mycobacterium chelonae infection that occurred after autologous fat injection. Patients were treated as infection that resistant to com...

The author prefers autologous tissue from a combined SMAS/fat graft for lip augmentation. However, he considers Alloderm the best alternative. Here he describes his technique and compares Alloderm with other available materials.