This paper presents high temperature measurements using a Brillouin scattering-based fiber optic sensor and the application of the measured temperatures and building code recommended material parameters into enhanced thermomechanical analysis of simply supported steel beams subjected to combined thermal and mechanical loading. The distributed temperature sensor captures detailed, nonuniform tem...

ELECTION of a genotype which gives rise to similar phenotypes in different environments is one evolutionary strategy which may result in high adaptedness of a population to the environments in which it lives. Presumably, the stability of certain traits is the outcome of a long history of natural selection tending towards an adaptive phenotype. Several investigators have attempted to select stra...

The Stubble-stubbloid (Sb-sbd) gene is required for ecdysone-regulated epithelial morphogenesis of imaginal tissues during Drosophila metamorphosis. Mutations in Sb-sbd are associated with defects in apical cell shape changes critical for the evagination of the leg imaginal disc and with defects in assembly and extension of parallel actin bundles in growing mechanosensory bristles. The Sb-sbd g...

The Notch receptor is the central element in a cell signaling mechanism controlling a broad spectrum of cell fate choices. Genetic modifier screens in Drosophila and subsequent molecular studies have identified several Notch pathway components, but the biochemical nature of signaling is still elusive. Here, we report the results of a genetic modifier screen of the bristle phenotype of a gain-of...

this paper deals with the solution of a column with balcony loads. it is intended to determine the expressions for deflections and bending moments of the sections of a column under the action of transmitted loads from a balcony loaded at its free end by a force «p» and rigidly connected to the column somewhere between its ends. the action of this load on the column is equivalent to that of the ...

The Siah proteins, mammalian homologues of the Drosophila Sina protein, function as E3 ubiquitin ligase enzymes and target a wide range of cellular proteins for degradation. Here, I investigate the in vivo function of the fly protein, Sina-Homologue (SinaH), which is highly similar to Sina. Flies that completely lack SinaH are viable and in combination with a mutation in the gene, Ebi, show an ...