In navigating the currently troubled waters of inflation and rising cost living, politicians are tempted to treat symptoms—offsetting increasing expenses with subsidies expanding welfare programmes. But one should also cause. The cause is not Russian aggression towards Ukraine. That a symptom—a symptom weakness Europe West, either real or perceived. This be addressed. 2022 power politics made c...

Insomnia has a major impact on human health, performance, economic productivity and quality of life.1,2 Insomnia chronic or severe enough to merit treatment occurs in 8–14% of the general population.3 There are few specialised sleep clinics in Great Britain other than respiratory ones (eg for obstructive sleep apnoea syndrome (OSAS)), most clinicians do not have easy access to psychological tre...

BACKGROUND Robotic cholecystectomy (RC) using port sites in the lower abdominal area (T12-L1) rather than the upper abdomen has recently been introduced as an alternative procedure for laparoscopic cholecystectomy. Therefore, we investigated the time course of different components of pain and the analgesic effect of the bilateral ultrasound-guided split injection technique for rectus sheath blo...

The aim of this work was to evaluate the effect of a cycle of estivation and awakening on free radical metabolism in selected organs of the land snail Helix aspersa. Estivation for 20 days induced a 4.9- and 1.8-fold increase in selenium-dependent glutathione peroxidase activity (Se-GPX) and in total glutathione levels (GSH-eq), respectively, in hepatopancreas when compared to activity in activ...

Aspirin is used for cardiovascular disease (CVD) prevention by millions of patients on a daily basis. Previous studies suggested that aspirin intake at bedtime reduces blood pressure compared with intake on awakening. This has never been studied in patients with CVD. Moreover, platelet reactivity and CVD incidence is highest during morning hours. Bedtime aspirin intake may attenuate morning pla...

Pregnancy is associated with increased basal cortisol levels, and decreased hypothalamic-pituitary-adrenal (HPA) axis reactivity. The cortisol awakening response (CAR) is a measure of HPA-axis reactivity which has been reported to be increased in patients with ongoing depressive disorder and in individuals with remitted depression. In this study, we investigated HPA-axis reactivity in pregnant ...