The dorso-ventral axis in zebrafish first becomes apparent at gastrulation, when the future ventral side appears thinner than the dorsal side. The exact time of establishment of the dorso-ventral axis is not known. We show here that the dorso-ventral axis is specified as early as the 32 cell stage. Using lithium as a marker for dorso-ventral asymmetry, we show that lithium-sensitivity is a char...

Long-term success on total knee arthroplasty (TKA) depends mainly on restitution of the limb’s mechanical axis and appropriate balance of soft tissue, as these factors optimize the load distribution to the interfaces [1-4]. Almost all patients with osteoarthritis have some degree of articular deformity, in varus or valgus, associated or not to certain ligament instability. In most cases, conven...

A gain-scheduled trajectory control is exemplary presented for two of six available axes of an overhead crane that allows for positioning and inclining the crane load according to specified trajectories. Besides its tracking capabilities, the proposed control provides an active oscillation damping. The overall control structure consists of independent axis controllers, which are adapted to meas...

A practical calibration method for multi-axis force/torque sensors is presented. The on-site calibration of multi-axis force/torque sensors can be difficult, as many methods require precise knowledge of all force and moment components resulting from an applied load. Here, a method is presented that requires knowledge of only one component of the applied force. The method is based on decompositi...

Figure 1. Fluctuation of capsid protein homology to Sabin 2 and viral stool excretion in serial stool samples from the paralysis case-patient (PC, left) and the asymptomatic contact with prolonged excretion (AC3, right). Time of sampling is included in the x-axis; homology percentage with respect to original Sabin 2 strain (X00595) and viral load in stools are in y-axis, left and right, respect...

<span lang="EN-US">This <span>paper aims to develop the sliding mode control (SMC) scheme in sensorless permanent magnet synchronous machine (PMSM) drives replace conventional proportional integral (PI) speed control. The SMC is formulated based on surface of error. And error corrected concept Lyapunov stability. designed with load torque observer so that disturbance can be estimate...

objective(s): to explore the correlation between expression patterns and functions of mir-383 and ldha in hepatocellular cancer (hcc). materials and methods: we detected the expression of mir-383 and ldha in 30 hcc tissues and their matched adjacent normal tissues using qrt-pcr. then we performed mtt assay, foci formation assay, transwell migration assay, glucose uptake assay and lactate produc...

Cancer associated fibroblasts (CAFs) in the tumor microenvironment (TME) play a critical role in tumor progression. We and others have demonstrated that stromal fibroblasts can transform adjacent epithelial cancer cells in vivo. Cancer cells and stromal cells interact through physical contact, mediated by soluble factors, insoluble extracellular matrices (ECMs) or extracellular vesicles (EVs) i...

BACKGROUND Most biomechanical studies for evaluation of the structural properties of meniscal repairs have been performed in tensile loading scenarios perpendicular to the circumferential meniscal fibers. However, meniscal repair constructs are also exposed to shear forces parallel to the circumferential meniscal fibers during healing, particularly in the midportion of the meniscus. HYPOTHESI...

OBJECTIVES This study compared the mechanical properties of various instruments for canal exploration and glide-path preparations. MATERIALS AND METHODS The buckling resistance, bending stiffness, ultimate torsional strength, and fracture angle under torsional load were compared for C+ file (CP, Dentsply Maillefer), M access K-file (MA, Dentsply Maillefer), Mani K-file (MN, Mani), and NiTiFle...