The purpose of this work is to review data on the biological effectiveness probiotics, their mechanisms action, and prospects for development new-generation preparations. Scientific practical justification symbiotic drugs a new generation – metabiotics as continuation probiotic concept given. authors discuss literature own results, which allow them propose approaches creation drugs. scientifica...

One of the most significant challenges within production probiotic products is survival and functionality bacteria during processing shelf life. In this research, bacterium Bifidobacterium bifidum was used as adjunct culture for Iranian white cheese containing different percentages Allium ampeloprasum L. ssp. iranicum Wendelbo extracts (1% 2% in fresh dried form). The effects plant extract on b...

AIM To characterize the bifidobacterial microbiota of the colonic mucosa in patients with colon cancer, inflammatory bowel disease or diverticuitis. METHODS A sample of the distal colonic mucosa was taken during surgery from a total of 34 patients, twenty-one with diagnosed colorectal cancer, nine with diverticulitis and four with inflammatory bowel disease, requiring surgery for their condit...

The anti-infectious activity of probiotic Bifidobacteria against Shiga toxin-producing Escherichia coli (STEC) O157:H7 was examined in a fatal mouse STEC infection model. Stable colonization of the murine intestines was achieved by the oral administration of Bifidobacterium breve strain Yakult (naturally resistant to streptomycin sulfate) as long as the mice were treated with streptomycin in th...

the aim of this study was to determine the suitability of different doses (0, 0.4, 0.8 and 1.2%) of coffee extract on fermentation and survival of lactobacillus acidophilus and bifidobacterium bifidum in milk and yoghurt. the produced samples were examined in terms of ph, acidity and microbial count during incubation period and permanence. the number of lactobacillus acidophilus and bifidobacte...