Beta-hemolysin production by group B streptococci (GBS) is speculated to be a major virulence factor of the organism. A virulent, beta-hemolytic group B streptococcus strain was mutagenized with the self-conjugative transposon Tn916 to derive isogenic strains with mutations only in the gene(s) responsible for beta-hemolysin biosynthesis. There was no significant difference between the virulence...

Mannose-binding lectin (MBL) is a collagenous serum lectin believed to be of importance in innate immunity. Genetically determined low levels of the protein are known to predispose to infections. In this study the binding of purified MBL to pathogens isolated from immunocompromised children was investigated by flow cytometry. Diverse Candida species, Aspergillus fumigatus, Staphylococcus aureus...

DEMONSTRATION OF BLOOD GROUP SUBSTANCE A BOUND TO PASTEURELLA PESTIS OBJECTIVE To determine the source, occurrence and location of human blood group antigens in P. pestis vaccines, and to quantitate the hemolytic potency of rabbit anti-P. pestis sera for human type A, B and 0 red cells.

Background Autoimmune hemolytic anemia is a hematologic disorder that is rarely observed in infants and young children. Most of the cases are associated with viral or bacterial infections. In some cases, AIHA can be characterized by a chronic course and an unsatisfactory control of hemolysis, thus requiring prolonged immunosuppressive therapy. Case report Especially in children younger...

Two methods of typing group A hemolytic streptococci have been described: slide agglutination and anti-M precipitin tests. The first, developed by Griffith (1), is more extensively used. I t has the distinct advantages of requiring small amounts of serum and culture, and of a quick reaction time when all conditions are favorable. I t has certain disadvantages: The granular growth of some strain...

Background. ABO hemolytic disease of the newborn is the most common hemolytic consequence of maternofetal blood group incompatibility restricted mostly to non-group-O babies of group O mothers with immune anti-A or anti-B antibodies. Aim. We estimated the risk of ABO HDN with view to determining need for routine screening for ABO incompatibility between mother and fetus. Materials and Methods. ...

Erysipelas is an acute dermo-hypodermic (non-necrotizing) infection of bacterial origin, mainly group A beta-hemolytic streptococcus. The lower limbs are affected in more than 80% cases and the risk factors identified skin barrier breakdown, lymphedema obesity. Diagnosis clinical based on association inflammatory plaque with fever, lymphangitis, lymphadenopathy leukocytosis. Bacteriology genera...

Streptococcus dysgalactiae subsp. equisimilis belongs to the β-hemolytic group C and G pyogenic group of streptococci. Here, we report the draft genome of the S. dysgalactiae subsp. equisimilis strain C161L1 from Vellore, a region in southern India with a high incidence rate of S. dysgalactiae subsp. equisimilis infection. This genome is 2.1 Mb long, with a 39.82% G+C content, and encodes 2,022...

hepatitis a is common in children and usually is a self-limiting disease.  although extrahepatic and hematological immune manifestations following acute hepatitis a virus (hav) infection have rarely been reported, they are frequently observed in other viral hepatitis. in this paper, we report the case of a 3-year-old girl who developed immune thrombocytopenic purpura (itp) and hemolytic anemia ...