We consider the problem of one-dimensional topological com-paction with jog insertions. Combining both geometric and graph the-oretic approaches we present a faster and simpler algorithm, improving over previous results. The compaction algorithm takes as input a sketch consisting of a set F of features and a set W of wires, and minimizes the horizontal width of the sketch while maintaining its ...

Phosphoinositides play important roles in regulating the cytoskeleton and vesicle trafficking, potentially important processes at the cleavage furrow. However, it remains unclear which, if any, of the phosphoinositides play a role during cytokinesis. A systematic analysis to determine if any of the phosphoinositides might be present or of functional importance at the cleavage furrow has not bee...

Cell division is achieved by a plasma membrane furrow that must ingress between the segregating chromosomes during anaphase [1-3]. The force that drives furrow ingression is generated by the actomyosin cytoskeleton, which is linked to the membrane by an as yet undefined molecular mechanism. A key component of the membrane furrow is anillin. Upon targeting to the furrow through its pleckstrin ho...

Calendering is a key yet complex manufacturing process that has varied effects on the Li-ion battery cell performance. Finding optimal compaction can require many experiments if using traditional one-factor-at-a-time method, which would be both and resource intensive. Design of Experiments (DoE) coupled with modeling via multiple linear regression (MLR) are used in this study to better understa...

We studied reorganization of actin-myosin cytoskeleton at the growing ends of the cleavage furrow of Xenopus eggs in order to understand how the contractile ring is formed during cytokinesis. Reorganization of F-actin structures during the furrow formation was demonstrated by rhodamine-phalloidin staining of the cleavage furrow and by time-lapse scanning with laser scanning microscopy of F-acti...

Insight into crumpling or compaction of one-dimensional objects is important for understanding biopolymer packaging and designing innovative technological devices. By compacting various types of wires in rigid confinements and characterizing the morphology of the resulting crumpled structures, here, we report how friction, plasticity and torsion enhance disorder, leading to a transition from co...