Neutrophil infiltration constitutes the first step in wound healing, although their timely clearance by macrophage engulfment, or efferocytosis, is critical for efficient tissue repair. However, the specific mechanism for neutrophil clearance in wound healing remains undefined. Here we uncover a key role for CCN1 in neutrophil efferocytosis by acting as a bridging molecule that binds phosphatid...

Wound healing is a critical physiological function needed for survival in all marine organisms. However, it is particularly critical in organisms like corals, which cannot escape predators. In this study, I characterized the gross morphology of wound healing in Pocillopora damicornis and Acropora hyacinthus found in two pools with distinct previously documented temperature profiles in Ofu, Amer...

background : recurrent aphthous stomatitis (ras) is one of the most common mucosal ulcerative of oral cavity. role of immune system, especially cytokines in immunopathogenesis of aphthous stomatitis was not highly considered. the aim of this study was to evaluate the levels of salivary cytokines, including vegf-r3, tgf-&beta1;, tnf-α, and il-17a/f in patients with ras in two clinical stages, ul...

OBJECTIVE This article illustrates the use of the evidence-based process in clinical practice to answer questions that arose when a patient presented with dental trauma. BACKGROUND The patient had avulsion of the maxillary right central incisor and lateral luxation and alveolar bone fracture partially encasing the roots of the maxillary left central and lateral incisors. At the emergency trea...

BACKGROUND AND AIM Despite improvements in surgical revascularisation, limitations like anatomical factors or atherosclerosis limit the success of revascularisation in diabetic patients with critical limb ischaemia. Stem cells were shown to improve microcirculation in published studies. The aim of this study was to evaluate safety, feasibility and efficacy of transplantation of bone marrow deri...

the application of critical pedagogy in educational contexts has received adequate research attention over the last decades. the main focus of this strand of research has, however, been on raising awareness of the educators. nevertheless, little is known about the consequences of the violation of critical pedagogy principles from efl teacher trainers’ perspectives. to begin to address this gap ...

Background: Ethnomedicinal plants are of interest for treatment of various wound types. Objective: This study aimed to evaluate burn wound healing potential of the hydro-alcoholic extract of the flowers of Lilium candidum L. in rats. Methods: DPPH free radical scavenging power, total flavonoids, and the phenolic content of the extract were evaluated. Following burn wound induction, 30 Wistar ra...

Standard Model Higgs pair production at e+e− colliders has the capability to determine the Higgs boson self-coupling λ. I present a detailed analysis of the e+e− → ZHH and e+e− → νν̄HH signal channels, and the relevant background processes, for future e+e− linear colliders with center of mass energies of √ s = 0.5 TeV, 1 TeV, and 3 TeV. Special attention is given to the role non-resonant Feynman...

BACKGROUND Bacterial biofilm is recognized as a major detriment to wound healing. The efficacy of traditional wound care against biofilm has never been studied. The authors evaluated the effect of clinical strategies against biofilm-infected wounds in a quantitative, in vivo model. METHODS Using a rabbit ear biofilm model, wounds were inoculated with Pseudomonas aeruginosa or left as uninfect...