Present study investigates the cognitive effects of BME on memory impairment in AD induced mice. Male Albino mice, Musmusculus of one month old weighing 20 ± 2 grams, were used as experimental model and were maintained according to ethical guidelines for animal protection and welfare. Mice were divided in to four groups as follows: Group I: Control mice; Group II: mice treated with BME; Group I...

CDRI-08 is a standardized bacoside enriched ethanolic extract of Bacopa monnieri, a nootropic plant. We reported that CDRI-08 attenuated oxidative stress and memory impairment in mice, induced by a flame retardant, PBDE-209. In order to explore the mechanism, present study was designed to examine the role of CDRI-08 on the expression of NMDAR1 (NR1) and the binding of REST/NRSF to NR1 promoter ...

Bacopa monniera Wettst. (syn. Herpestis monniera L.; Hindi - Brahmi) is classified in Ayurveda, the classical Indian system of medicine, as Medhyarasayana, a group of plant derived drugs used as nervine tonics to promote mental health and improve memory and intellect. Earlier experimental and clinical studies have demonstrated the memory-promoting action of the plant extracts and that of its ac...

Bacopa monnieri (L.) Wettst. (family Scrophulariaceae) is a creeping, glabrous, succulent herb, rooting at nodes whose habitat includes wetlands and muddy shores. Commonly known as Brahmi, the plant is 10-30 cm long with 1-2 mm thick, soft, glabrous stem having ascending branches. The leaves are 0.6-2.5 cm long and 3-8 mm broad. Flowers of brahmi are white or pale-bluish in colour, axillary, so...