It is now well established that bacteria communicate through the secretion and uptake of small diffusable molecules. These chemical cues, or signals, are often used by bacteria to coordinate phenotypic expression and this mechanism of regulation presumably provides them with a competitive advantage in their natural environment. Examples of coordinated behaviors of marine bacteria which are regu...

Endophytes have an intimate and often symbiotic interaction with their hosts. Less is known about the composition and function of endophytes in trees. In order to evaluate our hypothesis that plant genotype and origin have a strong impact on both, endophytes of leaves from 10 Olea europaea L. cultivars from the Mediterranean basin growing at a single agricultural site in Spain and from nine wil...

Plant-associated bacteria fulfill important functions for plant growth and health. However, our knowledge about the impact of bacterial treatments on the host's microbiome and physiology is limited. The present study was conducted to assess the impact of bacterial inoculants on the microbiome of chamomile plants Chamomilla recutita (L.) Rauschert grown in a field under organic management in Egy...

Mucosal surfaces, such as the lung and intestine, are lined by a monolayer of epithelia that provides tissue barrier and transport function. It is recently appreciated that a common feature of inflammatory processes within the mucosa is hypoxia (so-called inflammatory hypoxia). Given the strong association between bacterial translocation and mucosal inflammatory disease, we hypothesized that in...

The combination of levofloxacin and α1 adrenergic antagonist treatment is the current preferred choice for both bacterial and non-bacterial prostatitis. The aim of this study is to explore the influence of α1 adrenergic antagonists on the pharmacokinetics of levofloxacin using rat models with acute bacterial prostatitis (ABP) induced by direct injection with Escherichia coli (ATCC25922). A tota...

The increasing emergence of multiple drug resistant TB (MDR-TB) and extensively drug-resistant TB poses a serious threat to the control of tuberculosis disease. Furthermore, it is reported that 79% of MDRTB cases are ‘super strains’. Here is the Aspartyl beta-semi aldehyde dehydrogenase (ASADH) is an important enzyme, occupying the first branch position of the biosynthetic pathway of the aspart...

There is a lack of guidelines for preoperative dosing opioid and nonopioid pain medications surgical patients, which can lead to suboptimal control. The Society Perioperative Assessment Quality Improvement identified analgesics as an area in consensus could improve patient care. aim this guideline provide that will allow perioperative physicians make optimal recommendations regarding medication...

background: radioprotective capability of histamine h2 receptor antagonists have been shown in several in vivo studies mainly using animal models. however, to verify the effectiveness of these agents in clinical applications, studies should be performed on human cells. in the present study radioprotective properties of these agents was examined in vitro on human lymphocytes using metaphase anal...

Factor Xa antagonists are used increasingly frequently for prevention and treatment of venous thromboembolic events stroke systemic emboli in patients with non-valvular atrial fibrillation. Individual characteristics patient, a need prolonged or life-long treatment, concomitant diseases, the use other drugs interacting anticoagulants increase risk side effects anticoagulation. We analyzed curre...