The amino acid glycine strongly destabilizes a-helical structure in proteins as well as in model helical peptides. We have investigated the role of a single glycine substitution in a helical host peptide system. Quantitatively, a single glycine leucine substitution has about one-third of the effect on the stability of helix as does triple substitution of these residues in the middle of the heli...

Plas t ic i t y can be broadly defined as the capacity for any type of phenotypic change to occur during life. It is often argued that one of the main advantages of plasticity for individuals in evolving populations is adaptation to changing environments (see, e.g., Johnson 1982, Belew 1990). This is independent of other, less direct forms of interaction between evolution and plasticity, such a...

This paper attempts, using data from the British Labour Force Survey 1996, to examine to what extent differences in labour market outcomes between able-bodied and disabled men may be attributed to differences in endowments of human capital and associated productivity differences. Both labour force participation and selectivity corrected human capital equations are estimated and decomposition te...