For the past two decades, evidence-based medicine (EBM), or the reliance on current scientific evidence to reach medical decisions, has been embraced as a new paradigm to standardize clinical care. Drawing from in-depth interviews with seventeen pediatric residents in two residency programs, we evaluate the extent to which the medical sociology scholarship on uncertainty analytically elucidates...

Introduction As the current debates throughout the US attest, there are wide disagreements about the shape of future US health care delivery. Nevertheless, a general consensus has emerged about the need for more efficient interventions that are based on reliable scientific evidence. This need has been filled by evidence-based medicine (EBM), which employs meta-analyses and randomized controlled...

This is a confession building on a conversation with David Sackett in 2004 when I shared with him some personal adventures in evidence-based medicine (EBM), the movement that he had spearheaded. The narrative is expanded with what ensued in the subsequent 12 years. EBM has become far more recognized and adopted in many places, but not everywhere, for example, it never acquired much influence in...

The reigning paradigm underlying the work of physicians is evidence-based medicine (EBM). Since the early 1990s, evidence-based clinical practice guidelines addressing the management of asthma have been widely disseminated. In a 2009 survey of US primary care physicians, 78% reported using asthma guidelines (1). Despite an array of clinical interventions rooted in EBM, asthma attacks, emergency...

Evidence Based Medicine (EBM) is being taught in many medical universities around the world, however many studies have reported obstacles for effective EBM teaching. In this study we aim to evaluate the obstacles of teaching EBM in Iranian Medical Universities which have made slow progress in EBM. A qualitative descriptive study with content analysis was designed to thoroughly and deeply discus...

BACKGROUND As the overall evidence for the effectiveness of teaching of evidence based medicine (EBM) is not strong, and the impact of cultural and societal influences on teaching method is poorly understood, we undertook a randomised-controlled trial to test the effectiveness and learning satisfaction with two different EBM teaching methods (usual teaching vs. problem based learning (PBL)) for...

Experimental Biology and Medicine Nurbay Ates, Gul Ilbay and Deniz Sahin Application Suppression of Generalized Seizures Activity by Intrathalamic 2-Chloroadenosine 2005, 230:501-505. Experimental Biology and Medicine http://ebm.rsmjournals.com/content/230/7/501 Updated information and services can be found at: http://ebm.rsmjournals.com/content/230/7/501#BIBL This article cites 34 articles, 4 ...

A wide spectrum of alterations in mitochondria and mitochon-drial DNA (mtDNA) with aging has been observed in animals and humans. These include (i) decline in mitochondrial respiratory function; (ii) increase in mitochondrial production of reactive oxygen species (ROS) and the extent of oxidative damage to DNA, proteins, and lipids; (iii) accumulation of point mutations and large-scale deletion...

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BACKGROUND Evidence based medicine (EBM) is considered an integral part of medical training, but integration of teaching various EBM steps in everyday clinical practice is uncommon. Currently EBM is predominantly taught through theoretical courses, workshops and e-learning. However, clinical teachers lack confidence in teaching EBM in workplace and are often unsure of the existing opportunities...