A specific and reliable high-performance thin layer chromatography method with densitometry detection has been developed for the determination of naphazoline nitrate in nasal drops. The best separation of the basic analyte, without spot tailing, was achieved by using a mobile phase composed of acetonitrile-water (60:40, v/v), adding 1.5 % (v/v) imidazolium-class ionic liquid and covering the pl...

1-Alkyl-3-methylimidazolium-based ionic liquids (tetrafluoroborate, L-(þ)-lactate and ethyl sulfate) were used as mobile phase additives to assess the effect of its anionic part on the retention mechanism of perazine in pharmaceutical formulation in reversed-phase highperformance thin-layer chromatography (RP-HPTLC) method. In all cases, significant changes and improvements in the retention fac...

A review of the relevant literature on 1-alkyl-1-methylpyrrolidinium-based ionic liquids has been presented. The phase diagrams for the binary systems of {1-ethyl-1-methylpyrrolidinium trifluoromethanesulfonate (triflate) [EMPYR][CF(3)SO(3)] + water, or + 1-butanol} and for the binary systems of {1-propyl-1-methylpyrrolidinium trifluoromethanesulfonate (triflate) [PMPYR][CF(3)SO(3)] + water, or...

A carbon nanocomposite electrode has been designed by incorporation of montmorillonite nanoclayinto the carbon ionic liquid electrode for the electrochemical determination of amitriptiline . The surface ofthe proposed electrode was characterized by scanning electron microscopy. The presence of ionic liquid asa binder is believed to be responsible for the electrocatalytic activity of the propose...

We report on how the dynamical and structural properties of the ionic liquid 1-hexyl-3-methylimidazolium bis(trifluoromethanesulfonyl)imide (C6C1ImTFSI) change upon different degrees of confinement in silica gels. The apparent diffusion coefficients of the individual ions are measured by (1)H and (19)F pulsed field gradient nuclear magnetic resonance (PFG-NMR) spectroscopy, while the intermolec...

An affinity ionic liquid, based on biomolecular recognition, was developed and found to be capable of quantitative partitioning of biomacromolecules from aqueous buffer to ionic liquid.

Dispersion of graphene sheets in ionic liquid 1-butyl-3-methylimidazolium hexafluorophosphate was successfully achieved with the aid of a polymerized ionic liquid (PIL).