(TDDS), additionally called ‘ Transdermal patches,’ square measures dose form design to deliver a The human skin is readily accessible surface for drug delivery. Drug Delivery Systems therapeutically effective quantity of across patients skin. In order therapeutics agents through the systemic effect, comprehensive morphological , biophysical and physicochemical properties are be considered. del...

Multiobjective optimization problems are ubiquitous in real-world science, engineering, and design problems. It is not uncommon that the objective functions as a black box, evaluation of which usually involve time-consuming and/or costly physical experiments. Data-driven evolutionary can be used to search for set nondominated tradeoff solutions, where expensive approximated surrogate model. In ...

background: we have validated the monitor unit calculations from a commercially available treatment planning system (tps) for three intensity modulated radiotherapy (imrt) planning techniques for tangential breast irradiation by using ionization chamber measurements. materials and methods: treatment plans were generated for forty-two breast patients by a forward planned field in field technique...

nowadays, environment-sensitive smart drug delivery systems have found diverse applications in pharmaceutical science and technology. these systems can respond to the environment stimuli such as temperature, pressure, ph, light, electrical and magnetical fields and etc. they can release the proper amount of drug in human body. among these systems, special attention and much research works have ...

objective(s): in a new approach, following the development in metal oxide chemistry, the ibuprofen as low water soluble nonsteroidal anti-inflammatory drug diffused into synthetic sol-gel derived nano porous g-alumina by an impregnation method in order to increase the solubility and control the drug release in physiological environment. methods: sol-gel method was utilized for the fabrication o...