Background: Prostate cancer is currently the third malignant disease in Iran and fifth common cancer worldwide. The aim of this study was to determine the expression of GPRC6A, E.cadherin, and ZEB1 genes in prostate cancer in comparison with benign tumor. Since early detection of cancer plays an important role in treatment, this study aims to identify the role of GPRC6A, E.cadherin and ZEB1 gen...

invasive apocrine carcinoma (iac) of the breast is a rare subtype of breast malignancy. its incidence is not well known, but it is approximately less than 1% to 4%. for these reasons, there are few reports and little information on the radiologic appearance of iac. furthermore, most of the case reports show malignant features which are similar to invasive ductal carcinoma (idc). we present a ra...

Objectives: 1. To evaluate the role of mammography and sonomammography independently and in combination and correlating with FNAC for early diagnosis of breast lesions. 2.Benign To study the characteristics of mammography and sonomammography in detecting breast lesions and differentiating from benign and malignant lesions. Methods: 100 female patients attending Department of Radio diagnosis wit...

PURPOSE To develop a near-infrared spectroscopic method to identify breast cancer biomarkers and to retrospectively determine if benign and malignant breast lesions could be distinguished by using this method. MATERIALS AND METHODS The study was HIPAA compliant and was approved by the university institutional review board. Written informed consent was obtained. By using self-referencing diffe...

Malignant peripheral nerve sheath tumor (MPNST) is a rare malignant tumor that develops either from a preexisting neurofibroma or de novo. The cell of origin is believed to be the Schwann cell and possibly other nerve sheath cells. In this report, we describe a rare case of MPNST that arise from the socket of second left maxillary molar that has been already extracted in a young man. He was ref...

Background: Salivary gland tumors form nearly 3% of head and neck tumors. Due to their large histological variety and vicinity to facial nerves, pre-operative diagnosis and differentiation of benign and malignant parotid tumors are a major challenge for radiologists. Objective: The majority of these tumors are benign; however, sometimes they tend to transform into a malignant form. Functional M...

Background: Schwannoma is a peripheral nerve sheath tumor originating from schwann cells. It is the most common neurogenic tumor of the posterior mediastinum. Pleural effusion is a rare presentation of benign schwannoma and it is mainly related to malignant tumors. Histologically, schwannoma as well as solitary fibrous tumor should be considered as a differential diagnosis of spindle cell lesio...

Posterior acoustic shadowing (PAS) can bias breast tumor segmentation and classification in ultrasound images. In this paper, half-contour features are proposed to classify benign and malignant breast tumors with PAS, considering the fact that the upper half of the tumor contour is less affected by PAS. Adaptive thresholding and disk expansion are employed to detect tumor contours. Based on the...

Background: Cytokines, chemokines, and chemokine receptors regulate the proliferation and survival of tumor cells, angiogenesis, and metastasis to other organs. This network of ligands and receptors has been used in molecular targeting of cancer. Methods: We compared the mRNA expression of CXCR3, CXCL-10, CXCR4, CXCL-12, IL-4, and IL-10 in tissues of benign and malignant ovarian tumors by qRT-P...

Breast cancer (BC) is the most frequent malignant neoplasia and leading cause of mortality for women. A timely diagnosis BC crucial to ensure best chances survival. Among various screening tools BC, antibodies directed towards self-antigens or tumor-associated antigens (autoantibodies) have emerged as an alternative image-based modalities. However, little attention has been paid global diversit...