The diphosphopyridine nucleotidase exchange reaction, whereby isonicotinic acid hydrazide can replace nicotinamide in the DPN’ molecule, was demonstrated by Zatman el al. (1). Since this reaction provided a possible explanation for the growth inhibition of Mycobacteria by isonicotinic acid hydrazide, methods for measuring DPN in Mywbacteria were investigated. It was found that acetone powder ex...

the uses of non-steroidal anti-inflammatory drugs (nsaids) are limited by a variety of side effects. so research on preparing new analgesic agents is important. according to some reports about the analgesic activity of hydrazide and hydrazine derivatives a new series of these compounds were synthesized in order to obtain new analgesic compounds. the final compounds 10a-10e and 15a-15d were prep...

New Schiff bases derivatives from lauric acid were synthesized through the condensation of dodecane methyl ester with hydrazine to give corresponding hydrazide, which react aromatic aldehyde afford dodecanehydrazide-hydrazones and carbon disulfide 1,3,4-oxadiazole-2-thion. The chemical structures confirmed by numerous characterization methods; including Infrared, Ultraviolet-Visible, 1H 13C Nuc...

N-substituted pyridine hydrazide (pyridine-2-carbonyl chloride and 4-chloro-benzoic acid hydrazide) undergoes hydrazide formation of the iminic carbon nitrogen double bond through its reaction with cobalt(II), nickel(II), and copper(II) metal salts in ethanol which are reported and characterized based on elemental analyses, IR, solid reflectance, magnetic moment, molar conductance, and thermal ...

BACKGROUND Hydrophobic polystyrene is the most common material for solid phase immunoassay. Proteins are immobilized on polystyrene by passive adsorption, which often causes considerable denaturation. Biological macromolecules were found to better retain their functional activity when immobilized on hydrophilic materials. Polyacrylamide is a common material for solid-phase carriers of biologica...

A selective and sensitive method for determination of copper in blood by adsorptive differential pulse cathodic stripping voltammetry is presented. The method is based on adsorptive accumulation of the complexes of Cu (II) ions with benzenesulfonyl hydrazide onto hanging mercury drop electrode (HMDE), followed by the reduction of the adsorbed species by differential pulse cathodic stripping vol...

Hypochlorous acid is the most powerful oxidant generated by neutrophils and is likely to contribute to the damage mediated by these inflammatory cells. The haem enzyme myeloperoxidase catalyses its production from hydrogen peroxide and chloride. 4-Aminobenzoic acid hydrazide (ABAH) is a potent inhibitor of hypochlorous acid production. In this investigation we show that, in the presence of hydr...