conclusion following splenectomy, thrombocytosis can predispose the patients to an increase in cerebral blood velocities more than respected with anemia. but by transcranial doppler ultrasonography no evidence of significant stenosis were found in intracerebral arteries to conclude that the beta-thalassemia major patients were more prone to the development of stroke secondary to this abnormalit...

A simple colorimetric beta-lactamase assay for quantifying Leishmania amastigotes in macrophages grown in microtiter plates has been reported. The beta-lactamase gene was integrated into the rRNA region of the genome, thereby allowing for high-level stable expression of the enzyme. Both visceral leishmaniasis (VL) and post-kala azar dermal leishmaniasis (PKDL) isolates were transfected with bet...

background: hb a2 is elevated in subjects with beta thalassemia minor but small percent of carriers have normal hb a2 with elevated levels of hbf (2-10%). this type of thalassemia is called delta beta thalassemia, and can be missed in pre-marriage hematologic consults or screening which leads to increased risk of child birth with beta thalassemia major. materials and methods: in this prospectiv...

Cystic hydatid disease is caused by cystic larval (metacestode) stages of Echinococcus granulosus. This parasite can potentially occur all over the world especially in Mediterranean and Middle East countries and some parts of Africa, Latin America and China which have major foci of human infections. The cyst wall of metacestodes consists of inner, middle and external layers. To date, little att...

Abstract Background Hypothyroidism usually appears in the second decade of life and is thought to be associated with iron overload in patients with thalassemia major. This study aimed to evaluate thyroid dysfunctions in patients with beta-thalassemia major. Materials and Methods This research is a descriptive – cross sectional study, carried out in 2009 to assess thyroid function in 100 p...

Abstract Background: Thalassemias are the most common inherited blood disorders caused by some mutations which can reduce the synthesis of globin chains. Iron overload and its organ deposition are responsible for functional abnormalities and tissue injury in patients who affected by β-thalassemia major. The aim of this case-control study was evaluation of hematological parameters, oxi...

background accident investigation programs are a necessary part in identification of risks and management of the business process. objectives one of the most important features of such programs is the analysis technique for identifying the root causes of accidents in order to prevent their recurrences. analytical hierarchy process (ahp) was used to compare management oversight and risk tree (mo...

Background Frequent blood transfusion is often associated with iron overload. Proper use of iron chelators to treat iron overload requires an accurate measurement of iron levels. Magnetic resonance T2-star (T2* MRI) can measure iron level in the heart and liver. Our goal was to see whether an association exists between serum ferritin level and T2* MRI in patients with major beta thalassemia. ...