We evaluated the use of ion-exclusion chromatographic systems for analyzing the behavior of inorganic ions (e.g., bicarbonate, sulfate, chloride, nitrate, phosphate, dissolved silicate, sodium, ammonium, potassium, magnesium, and calcium ions) in a suburban river located in Jakarta, Indonesia. Carbonate, phosphate, and silicate ion concentrations were determined using ion-exclusion chromatograp...

Balance studies have been carried out to evaluate the influence of vasopressin-induced volume expansion on acid-base equilibrium in normal dogs and in dogs with steady-state metabolic acidosis induced by the administration of 5-7 mmoles/kg per day of hydrochloric acid.Hypotonic expansion in dogs with metabolic acidosis (mean plasma bicarbonate concentration 14 mEq/liter) produced a marked incre...

Using ion-exchange resins, a multiple-unit type of oral floating dosage system has been prepared to prolong gastric emptying time of dosage form. The system is composed of beads of drug-resin complex, which are loaded with bicarbonate ions and coated with a hydrophobic polymer. The system is so designed that when the beads reach the stomach, chloride ions are exchanged with bicarbonate and drug...

1. Ammonia absorption has been studied in closed loops of rat jejunum, ileum and colon. 2. Ammonia absorption was significantly greater from solutions buffered at higher pH. Absorption was also greater in the presence of the bicarbonate ion, and this effect was not due solely to the influence of bicarbonate upon the initial pH of the solutions studied. In the presence of ammonia net bicarbonate...

INTRODUCTION: The molecular probes used in hyperpolarized C spectroscopy have important advantages over contrast agents currently in clinical use, expected to have little or no toxicity in humans, even at relatively high concentrations. This feature is particularly appealing given recent concerns about contrast nephropathy associated with iodinated CT contrast, as well as nephrogenic systemic f...

Ion-trapping theory predicts that alkalinization of tumor extracellular pH will enhance the anti-tumor activity of weak-base chemotherapeutics. We have previously demonstrated that chronic and acute treatment of tumor-bearing mice with sodium bicarbonate results in tumor-specific alkalinization of extracellular pH. Furthermore, bicarbonate pretreatment enhances the anti-tumor activity of doxoru...

Multielectrode sensor arrays and bi-sensor systems designed for short and/or real-time concentration measurements of sodium, potassium, chloride, bicarbonate and pH are presented. The systems used for routine measurements in a small volume of blood and in biological liquids bathing a living human bronchial epithelial cell monolayer to characterize ion-fluxes are in focus [1, 2]. Several applica...

Higher plants, algae, and cyanobacteria are known to require bicarbonate ions for electron flow from the first stable electron acceptor quinone QA to the second electron acceptor quinone QB, and to the intersystem quinone pool. It has been suggested that in Photosystem II of oxygenic photosynthesis, bicarbonate ion functions to maintain the reaction center in a proper conformation and, perhaps,...