BACKGROUND Risk factors for congenital cryptorchidism were investigated in a prospective birth cohort study in Denmark and Finland from 1997 to 2001. METHODOLOGY AND PRINCIPAL FINDINGS In total, 2,496 boys were examined for cryptorchidism at birth (cryptorchid/healthy: 128/2,368) and three months old (33/2,215). Information on risk factors was obtained antenatally (questionnaire/interview) or...

Cryptorchidism is one of the most common genital defects in dogs. This study investigated the effects of abdominal cryptorchidism on morphology, cell proliferation, and Sertoli cell condition in a dog with spontaneous unilateral cryptorchidism. Elective orchidectomy was performed on the abdominal right testis and the scrotal left testis. Significant reductions in numbers of spermatogonia, sperm...

BACKGROUND Anogenital distance (AGD) in animals is a sensitive biomarker of fetal endocrine disruption and the associated testicular dysgenesis syndrome (TDS). However, AGD in human infants with cryptorchidism and hypospadias, which are potential manifestations of TDS during childhood, is not clearly described. OBJECTIVE Our aim was to compare AGD in boys with cryptorchidism or hypospadias ag...

background: in most mammals, the testis is always maintained at a lower temperature than that in the abdomen, and exposure of the testis to body temperature causes degeneration of germ cells. objective: in this research, the long effect of heat exposure on sperm parameters and microstructure of mouse testis were investigated. cryptorchid mouse were induced by exposure to abdominal heat. materia...

BACKGROUND Cryptorchidism (undescended testes) is associated with poor male fertility, but can be alleviated and fertility preserved to some degree by early detection and treatment. Here we assess the influence of socio-occupational class, geographical region, maternal age and birth cohort on time to detection and correction of cryptorchidism. METHODS All boys born in Denmark, 1981 to 1987 or...

Objective- Release of free radicals and oxidants following increased temperature of testis in cryptorchidism, play an important role in the producing testicular damage. The present study investigated the role of vitamin C as an antioxidant in protecting the testis against damage in experimental unilateral cryptorchidism. Design- Experimental study Animals- Forty five male adult Wistar–Albino ...

Cryptorchidism: When the testes do not descend, the condition is called ‘cryptorchidism’. The condition occurs in about 3% of full-term infants and about 30% of premature infants. Untreated cryptorchidism on both sides results in sterility because the cells involved in the initial development of sperm are destroyed by the higher temperature of the pelvic cavity. The chance of testicular cancer ...