Pheochromocytoma in pregnancy is a rare condition with an estimated incidence of one in 54,000 pregnancies. Pheochromocytoma in the setting of multiple endocrine neoplasia (MEN) type 2A develops in approximately 40% of the patients with this germline mutation. MEN 2A patients with pheochromocytoma are often asymptomatic compared to those with nonsyndromic pheochromocytoma. We present a 28-year-...

BACKGROUND Recent advance of genetic testing has contributed to the diagnosis of hereditary pheochromocytoma and paraganglioma (PPGL). The clinical characteristics of hereditary PPGL are varying among the types of mutational genes. It is still difficult to specify the pathognomonic symptoms in the case of rare genetic mutations. Here, we report the case of synchronous bilateral pheochromocytoma...

pheochromocytoma is a catecholamine‑producing tumor. there are a very few reported cases of clinical pheochromocytoma. here, we report a 27‑year‑old woman para 1 live 1 with chief complaint of headache, confusion, nausea, and vomiting 2 days after cesarean section. she was anxious and had palpitation. on physical examination, fever, tachycardia, tachypnea, high blood pressure, and right thyroid...

The etiology and pathogenesis of renal cell carcinoma (RCC) are only partially understood. Key findings in hereditary RCC, which may be site specific or a component of a syndrome, have contributed to our current understanding. Important heritable syndromes of RCC are those associated with pheochromocytoma, especially von Hippel-Lindau disease (VHL) associated with germline VHL mutations, and ph...

Pheochromocytomas and paragangliomas are tumors of the autonomic nervous system; pheochromocytomas are tumors of the adrenal medulla, and paragangliomas are extraadrenal tumors arising from either the sympathetic nervous system or parasympathetic ganglia. It has previously been estimated that approximately 10%–15% of pheochromocytomas are due to hereditary causes. However, our increased underst...

A 7-year-old girl presented with decreased vision in both eyes for 1 month. Examination showed visual acuity of 20/50 and 20/60, no afferent pupillary defect, cecocentral scotomas, and bilateral optic disc edema with extensive peripapillary and macular exudates. Magnetic resonance imaging showed multiple cortical and subcortical white matter lesions. Both the laboratory workup and the systemic ...

Excess concentrations of catecholamines in pheochromocytoma can cause various clinical manifestations. There are few reports of pheochromocytoma presented with stress-induced cardiomyopathy (catecholamine-induced cardiomyopathy) after mild stress and the case of pheochromocytoma associated with nonocclusive stroke is more uncommon. We report a case of pheochromocytoma manifested repeated stress...

Introduction: The present study was aimed to assess the diagnostic performance of the two imaging methods of 131I-metaiodobenzylguanidine (131I-MIBG) and 99mTc-hydrazinonicotinyl-Tyr3-Octreotide (99mTc-HYNIC-TOC) in diagnosis and localization of pheochromocytoma and neuroblastoma. Methods: This study ...

Extra-adrenal pheochromocytoma is rare and presents variable symptoms. Its difficulty to diagnosis delays appropriate treatment. We would like to report an unusual case of extra-adrenal pheochromocytoma. The patient came to the emergency room with dyspnea, palpitation, and cyanosis. He had a history of hospitalization for Fontan operation due to congenital heart disease. Despite medication, his...

Pheochromocytoma is a rare cause of secondary hypertension. Presentation varies from asymptomatic to paroxysmal hypertension, palpitations, flushing, syncope, and even shock or death. Diagnosis is often delayed because pheochromocytoma is not considered a likely diagnosis. We present the case of a 47-year-old male that presented with hypertensive emergency. Several diagnostic tests were perform...