Introduction: During the neonatal period, metabolism of bilirubin is in transition from the fetal stage to the adult stage1. Uridine diphosphoglucuronyl transferase (UDPGT), an important liver enzyme for conjugation and excretion of bilirubin, is detectable at 18 – 20 weeks of gestation. UDPGT levels in full term neonates are usually less than 0.1% of adult values. Adult value of this enzyme ac...

Abstract Objective To elucidate the differences in etiology of dyskinetic cerebral palsy (DCP) between term-born and preterm-born children its relationship to functional outcomes. Methods We determined DCP based on clinical course brain MRI 163 136 children. Information about genetic abnormality was also collected if available. Functional outcomes were compared two major etiologies each group, ...

When exposed to light, bilirubin undergoes photoisomerization which are water-soluble and can be excreted in bile and urine. Photoisomerization starts as soon as the lights turned on, and risk of bilirubin encephalopathy is lower in infants who receive phototherapy even in the same serum bilirubin levels. Blue light is absorbed most readily if bilirubin is in a tube, but skin penetration and al...

conclusions the data from this cohort indicates that most of patients diagnosed with hcc present at late tumor and liver disease stages, when prognosis is usually dismal. regular cancer surveillance in cirrhotic patients might change the outcomes. further studies with results of treatment outcomes in this community are needed. background hepatocellular carcinoma (hcc) is one of the leading caus...

BACKGROUND Low birth weight and premature infants are at major risk for exaggerated hyperbilirubinaemia and jaundice that can lead to bilirubin encephalopathy. Phototherapy is the most common treatment for neonatal hyperbilirubinaemia and could be most effective in preventing the sequelae of hyperbilirubinaemia if initiated prophylactically. OBJECTIVES To evaluate the efficacy and safety of p...