The major components of our diet, namely, carbohydrates, fats, proteins, vitamins, and minerals provide for the building blocks besides serving as metabolic fuel to fulfil bioenergetic needs. Since they serve basic cellular needs, are considered ‘primary metabolites’. molecular biochemical pathways modulated by food diet well-established. Many phytochemicals referred ‘secondary metabolites’ not...

Volume 24 completes the presentation of methods applicable to the study of the biochemical and biophysical properties of photosynthetic and nitrogen fixing systems. The first part of this volume is concerned with the description of the physical and biochemical methods applicable to the identification of individual components of the photosynthetic system and the determination of their kinetic pa...

The serum or plasma biochemical profile is essential in the diagnosis and monitoring of systemic disease in veterinary medicine, but current reference intervals typically take no account of breed-specific differences. Breed-specific hematological phenotypes have been documented in the domestic dog, but little has been published on serum biochemical phenotypes in this species. Serum biochemical ...

Compatible solutes are components that can be quickly accumulated and degraded inside fungal cells. They do not disturb the functioning of proteins and protect the cell under adverse conditions. In this issue of the Biochemical Journal, Solomon and co-workers evaluate the role of mannitol, one of these components, in Stagonospora nodorum, a plant-pathogenic fungus, and find surprising effects o...

Recently, we showed the adenovirus proteinase interacts productively with its protein substrates in vitro and in vivo in nascent virus particles via one-dimensional diffusion along the viral DNA. The mechanism by which this occurs has heretofore been unknown. We show sliding of these proteins along DNA occurs on a new vehicle in molecular biology, a 'molecular sled' named pVIc. This 11-amino ac...

The antioxidant activities based on the free radical scavenging, reducing power, and bleaching inhibition were investigated for the three commonly used honeys in Malaysia, namely, tualang, gelam, and acacia honey. The antioxidant capacity of the honey samples was correlated with their biochemical constituents such as total phenol, total flavonoid content, and total water-soluble vitamins (vitam...

Protein complexes perform many important functions in the cell. Large-scale studies of protein-protein interactions have not only revealed new complexes but have also placed many proteins into multiple complexes. Whilst the advocates of hypothesis-free research touted the discovery of these shared components as new links between diverse cellular processes, critical commentators denounced many o...

BACKGROUND Obesity in pregnancy is associated with systemic inflammation, immunological changes and adverse maternal-fetal outcomes. Information on the association between maternal obesity and breast milk composition is scarce. This study describes changes and relationships between biochemical and immunological parameters of colostrum and serum of overweight and obese women. METHODS Colostrum...

Genome-enabled discoveries are the hallmark of 21st century biology, including major discoveries in the biosynthesis and regulation of plant metabolic pathways. Access to next generation sequencing technologies has enabled research on the biosynthesis of diverse plant metabolites, especially secondary metabolites, resulting in a broader understanding of not only the structural and regulatory ge...

Brownian Dynamics algorithms have been widely used for simulating systems in soft-condensed matter physics. In recent times, their application has been extended to the simulation of coarse-grained models of biochemical networks. In these models, components move by diffusion and interact with one another upon contact. However, when reactions are incorporated into a Brownian dynamics algorithm, c...