نتایج جستجو برای: bioequivalence
تعداد نتایج: 1898 فیلتر نتایج به سال:
Correspondence: E. Derom, Dept of Respiratory Diseases, University Hospital, De Pintelaan 185, B-9000 Gent, Belgium. It is generally accepted that inhalation therapy is the most effective way to treat patients with asthma or chronic obstructive pulmonary disease (COPD). Indeed, inhalation of relatively small doses of drug not only results in high, local concentrations in the airways the site of...
s, IndMed, and MedInd.
Background: Development of simple, rapid, and sensitive assay for the determination of loratadine in order to investigate its pharmacokinetic parameters in human plasma and its application in bioequivalence study of Loratadine 10mg Oral Disintegrated Tablets manufactured locally (test) and originally (Reference). Methods: After extraction of loratadine from human plasma, it was chromatographed ...
BACKGROUND The aim of this study was to determine the bioequivalence of generic (test) and branded (reference) formulations of betamethasone injectable suspension in healthy Iranian subjects for the purpose of meeting regulatory requirements for bioequivalence of the generic formulation in Iran. METHODS 24 healthy Iranian male volunteers were participated for this single-dose, randomized, ope...
Olanzapine is an atypical antipsychotic drug, used for the management of schizophrenia and for the treatment of moderate to severe mania associated with bipolar disorder. The objective of the present randomised, crossover study was to compare the bioavailability of olanzapine 10 mg/5 ml powder for oral suspension with olanzapine 10 mg orally disintegrating tablet. Eighteen healthy male voluntee...
Equivalence testing and corresponding confidence interval estimates are used to provide more enlightened statistical statements about parameter estimates by relating them to intervals of effect sizes deemed to be of scientific or practical importance rather than just to an effect size of zero. Equivalence tests and confidence interval estimates are based on a null hypothesis that a parameter es...
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