نتایج جستجو برای: biologic therapy
تعداد نتایج: 705849 فیلتر نتایج به سال:
Updated treatment recommendations for the therapy of rheumatoid arthritis (RA) in South Africa advocate early diagnosis, prompt initiation of disease-modifying anti-rheumatic drugs (DMARDs), and an intense treatment strategy where disease activity is assessed with a composite score such as the Simplified Disease Activity Index (SDAI). Frequent assessments and escalation of therapy are necessary...
OBJECTIVE To elaborate recommendations for the treatment of rheumatoid arthritis in Brazil. METHOD Literature review with articles' selection based on evidence and the expert opinion of the Rheumatoid Arthritis Committee of the Brazilian Society of Rheumatology. RESULTS AND CONCLUSIONS 1) The therapeutic decision should be shared with the patient; 2) immediately after the diagnosis, a disea...
Abstract Objectives The purpose of this analysis was to assess the frequency inadequate response (IR) over 1 year from biologic initiation among Crohn’s disease (CD) patients in United States using a claims-based algorithm. Baseline factors associated with IR were also analyzed. Methods This retrospective cohort study claims data HealthCore Integrated Research Database. Adult CD who initiated (...
Objectives: The aims of our study are to determine the new comorbidities appearing under biologic therapy, their prevalence, and factors implicated in appearance. Methods: It’s a multicentric historical-prospective cohort including 10 rheumatology departments Moroccan University Hospitals. data were collected from national register patients therapy supervised by Society Rheumatology. An electro...
Abstract INTRODUCTION Some inflammatory bowel disease (IBD) patients do not achieve remission with maximal medical therapy. We present a case of refractory UC who achieved clinical, endoscopic, and histologic after combining biologic small molecule CASE DESCRIPTION A 25-year-old Caucasian male was referred to our clinic for UC. Since diagnosis four years prior, he failed mesalamine, azathioprin...
A RECENT report from the Recombinant DNA Advisory Committee lists 393 approved human gene therapy protocols (www.od.nih.gov/oba/documents.htm). Of these, 33 are for infectious diseases, 49 for monogenic diseases (mostly cystic fibrosis), 237 for cancer, 35 for other disorders, and the remainder for nontherapeutic trials. Despite the serious nature of pain, both in terms of human suffering and e...
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