The possible involvement of a 15-kDa phosphotyrosyl protein, pp15, in insulin action was investigated by using the insulin-mimetic agent, vanadate. Vanadate, a phosphotyrosine phosphatase inhibitor, was found to mimic insulin in 3T3-L1 adipocytes by three criteria. First, kinetic and concentration-dependence studies verified the insulin-like effect of vanadate in activating 2-deoxyglucose uptak...

Monoclinic scheelite bismuth vanadate (BVO) microballs were prepared by a facile hydrothermal method and subsequently modified with 2 wt% of noble metals (NM = Au, Ag, Cu, Pt Pd) photodeposition route. All materials characterized diffuse reflectance spectroscopy (DRS), X-ray diffraction (XRD), photoelectron (XPS) Fourier-transform infrared (FTIR). The photocatalytic performance was investigated...

The insulin-mimetic effect of vanadate is well established, and vanadate has been shown to improve insulin sensitivity in diabetic rats and humans. Although the exact mechanism(s) remain undefined, we have previously demonstrated a direct relation of intracellular free magnesium (Mg(i)) levels to glucose disposal, to insulinemic responses following glucose loading, and to insulin-induced ionic ...

Abstract The street art murals ‘The Big Mother’ by Gola Hundun, the ‘Big Sacral Bird’ Kenor, ‘Oriental Carpet” H101 and “The Economy Subdues You” Zosen, belonging to Cooperative Popular Houses of Mancasale Coviolo in Reggio Emilia (Italy), were investigated use various mobile Raman spectrometers coupled different lasers micro-Raman spectroscopy on selected samples. study was made necessary evid...

Abstract A many-body large polaron, which is important for both fundamental physics and technological applications, has been predicted to occur in bismuth vanadate (BiVO 4 ). Herein, using a combination of high-resolution spectroscopic ellipsometry, X-ray absorption spectroscopy at the V L 3,2 - O K -edges, diffraction supported by theoretical calculations, we reveal new large-hole polaron W-do...

We present first-principles calculations of the electronic structure of BiVO4 at various levels of theory. In the calculations, we take into account a series of effects that affect the band gap, i.e., spin-orbit coupling, electron-hole interaction, nuclear quantum motions, and thermal vibrations. All these effects lead to a significant renormalization of the band gap. After including the releva...

X-ray fluorescence (XRF) spectroscopy was measured on duplicate libraries deposited on Si (without BiVO4) due to the overlap between the Ce Lα line (4.839 kV) from the coating and the V Kα line (4.952 kV) from the BiVO4. The x-ray beam was approximately 2 mm in diameter. Since the XRF sampling depth far exceeds the film thickness, XRF counts for each element were assumed to be proportional to t...

Direct measurements of the stiffness (elastic bending resistance) of demembranated sera urchin sperm flagella were made in the presence of MgATP2- and vanadate. Under these conditions, the flagellum is in a relaxed state, with a stiffness of approximately 0.9 x 10(-21) N m2, which is approximately 5% of the stiffness obtained in the rigor state in the absence of MgATP2-. MgADP- dose not substit...

Nitric oxide (NO) production by endothelial cells in response to bradykinin (Bk) treatment was markedly and synergistically enhanced by cotreatment with sodium orthovanadate (vanadate), a phosphotyrosine phosphatase inhibitor. This enhancement was blocked by tyrosine kinase inhibitors. Calcium ionophore- (A23187) activated production of NO was also enhanced by cotreatment with vanadate. No sign...