Porokeratosis is a rare genodermatosis based on chronic keratinization disorder histologically characterized by the presence of a cornoid lamella and various clinical manifestations. Five most commonly described types of poroketarosis are porokeratosis of Mibelli or ”classic” porokeratosis, disseminated superfi cial actinic porokeratosis, disseminated palmoplantar porokeratosis, linear porokera...

El síndrome de Bloch-Sulzberger o incontinencia pigmentaria es una genodermatosis infrecuente que afecta a los tejidos derivados del neuroectodermo. Esta patología herencia dominante, tiene penetrancia 100% y se encuentra ligada al cromosoma X. En pacientes género masculino suele ser letal, por lo la mayor parte casos reportados son mujeres diagnosticadas durante primera infancia. cuanto cuadro...

Mammalian organs are known to decarboxylate a number of n-amino acids. Of the mammalian decarboxylases, 3,4-dihydroxyphenylalanine decarboxylase is probably the most studied. Blaschko (1) reported values for DOPAl decarboxylase in .liver and kidney of several animal species. The enzyme was shown to be deactivated by dialysis and its activity restored by the addition of pyridoxal phosphate (2, 3...

It now seems reasonable to postulate that in the hypothalamus there exists a mechanism that is peculiarly concerned with the release of ovulating hormone and through which changes in the external environment and in the ovarian hormones may influence pituitary function. Markee et al. (1948) produced ovulation by instilling epinephrine directly into the pars distalis or into the third ventricle. ...

Mammalian organs are known to decarboxylate a number of n-amino acids. Of the mammalian decarboxylases, 3,4-dihydroxyphenylalanine decarboxylase is probably the most studied. Blaschko (1) reported values for DOPAl decarboxylase in .liver and kidney of several animal species. The enzyme was shown to be deactivated by dialysis and its activity restored by the addition of pyridoxal phosphate (2, 3...

Lichen striatus is a self-limiting inflammatory dermatosis that is characteristically distributed along the Blaschko lines. It is usually seen in children although cases, with different histopathological features, have been reported in adults. In view of the characteristic clinical features of the disease in adults—with its papulovesicular aspect—it is known as blaschkitis. Subsequently, differ...

Vitiligo is an autoimmune disease characterized by depigmentation of the skin due to destruction of melanocytes. Interferons have been used for the treatment of chronic hepatitis C and some malignancies. We report interferon alpha-2a-induced vitiligo in a male patient with chronic active hepatitis C. All skin lesions disappeared completely without requiring therapy after discontinuation of inte...

Object detection, or more generally pattern detection and recognition, can be based on many different principles. The objects can be described through their structure, shape, color, texture, etc. [Blaschko & Lampert (2009); Chen et al. (2004); Fidler & Leonardis (2007); Leibe et al. (2008); Lowe (1999); Serre et al. (2005); Viola & Jones (2001)]; therefore, a variety of object detection mechani...

MAMMALIAN liver and other organs contain an enzyme which catalyses the oxidation of adrenaline. By testing the ability of this enzyme to oxidize other amines of similar constitution it was found that certain groups in the adrenaline molecule, namely (a) the hydroxyl group in the side chain, (b) the phenolic hydroxyl groups and (c) the N-methyl group, were not essential for the oxidation to take...

Four related cows showed hairless streaks on various parts of the body with no correlation to the pigmentation pattern. The stripes occurred in a consistent pattern resembling the lines of Blaschko. The non-syndromic hairlessness phenotype observed occurred across three generations of a single family and was compatible with an X-linked mode of inheritance. Linkage analysis and subsequent whole ...