Phylostratigraphy is a computational framework for dating the emergence of DNA and protein sequences in a phylogeny. It has been extensively applied to make inferences on patterns of genome evolution, including patterns of disease gene evolution, ontogeny and de novo gene origination. Phylostratigraphy typically relies on BLAST searches along a species tree, but new simulation studies have rais...

Immunological phenotyping of blasts from over 200 children with acute lymphocytic leukemia (ALL) reveals both interpatient differences and phenotypic heterogeneity in the blast popula tion from individual patients. A battery of five independent lymphocyte differentiation markers, erythrocyte-forming ro settes, T-cell antigens, la-like antigens, the common ALL anti gen, and surface immunoglobuli...

  Purpose: Since explosive blasts continue to cause casualties in both civil and military environments, there is a need for an understanding of the mechanisms of blast trauma at the human organ level, plus a more detailed predictive methodology. The primary goal of this research was to develop a finite element model capable of predicting primary blast injury to the lung so as to assist in the d...

A linear superposition method was used for modeling the time history of the production blast vibrations and optimizing the blast sequence to reduce vibration levels in Sar-Cheshmeh copper mine, Kerman, Iran. A single-hole blast for modeling and two double-hole blasts with time delays of 25 and 65 ms between two holes for modeling validation were carried out. The generated vibrations were measur...

In order to determine whether antigenic patterns alter with disease progression and are thereby suggestive of impending blast crisis in chronic myelogenous leukemia. 50 bone marrow biopsy specimens from 32 patients were examined retrospectively using indirect immunoperoxidase labeling with three monoclonal antibodies that detect myeloid antigens. Monoclonal antibodies PMN1 3F6. PMN7C3. and PMN8...

plant growth promoting rhizobacteria (pgpr) are known to influence plant growth by various director indirect mechanisms. thirty–two strains were isolated from 15 soils sampled in central iran, byusing and comparing three different methods. the screening of soil samples by means of soil paste–plate method combined with isolation on mannitol agar proved to be the best strategy in terms ofreliabil...

Cereal Chem. 77(5):535–540 Observations in 1997 indicated a significant reduction in kernel bulk density and head rice yield of rice cultivar LaGrue due to blast (Pyricularia grisea). A more detailed study on rice cultivar M202 in 1998 confirmed such observations but it also showed negative effects of blast on other physical properties of rice. Rough rice from blast-infected panicles was drier ...

purpose: since explosive blasts continue to cause casualties in both civil and military environments, there is a need for an understanding of the mechanisms of blast trauma at the human organ level, plus a more detailed predictive methodology. the primary goal of this research was to develop a finite element model capable of predicting primary blast injury to the lung so as to assist in the dev...

Even in the tyrosine kinase inhibitors era, the prognosis of patients with chronic myeloid leukaemia in myeloid blast crisis remains dismal with few patients surviving longer than 6 months. Here we report the cases of 5 patients treated with the combination of 5-azacytidine and tyrosine kinase inhibitors for myeloid blast crisis CML. All patients achieved a complete haematological response incl...