The relationship between arterial and tissue PO2 is not well understood in the adult, let alone in the fetus. Figure 1 shows the pathway for oxygen through the maternal lungs and pulmonary circulation to the systemic circulation. For the fetus, there is an additional step of transfer across the placenta to fetal blood, and thence via the fetal heart to systemic circulation and fetal tissues. It...

Oxygen is an essential part of the living organism. It is transported from blood to the body tissue by the systematic circulation and large part of it is stored in the blood flowing in capillaries. In this work we discuss a mathematical model for oxygen transport in tissues. The governing equations are established assuming that the blood is flowing along a co-axial cylindrical capillary inside ...

Collateral circulation provides an alternative route for blood flow to reach ischemic tissue during a stroke. Blood flow through the cerebral collaterals is a critical predictor of clinical prognosis after stroke and response to recanalization, but data on collateral dynamics and collateral therapeutics are lacking. Here, we investigate the efficacy of a novel approach to collateral blood flow ...

The functional changes in respiration, circulation, blood composition and blood temperature were investigated in anesthetized dogs that were subjected to the inhalation of steam. The pathogenesis of the accompanying pulmonary congestion and edema was analyzed by measurements of: (a) pulmonary blood flow, (b) pressures in pulmonary artery and vein, (c) pulmonary blood (P32) volume, (d) electrica...

The functional changes in respiration, circulation, blood composition and blood temperature were investigated in anesthetized dogs that were subjected to the inhalation of steam. The pathogenesis of the accompanying pulmonary congestion and edema was analyzed by measurements of: (a) pulmonary blood flow, (b) pressures in pulmonary artery and vein, (c) pulmonary blood (P32) volume, (d) electrica...

BACKGROUND Blood transfusion is used to treat acute anemia with the goal of increasing blood oxygen-carrying capacity as determined by hematocrit (Hct) and oxygen delivery (DO2). However, increasing Hct also increases blood viscosity, which may thus lower DO2 if the arterial circulation is a rigid hydraulic system as the resistance to blood flow will increase. The net effect of transfusion on D...

application to circulation of the giraffe head. Am J Physiol Regul Integr Comp Physiol 256: R567–R571, 1989. 11. Hicks JW and Badeer HS. Gravity and the circulation: “open” vs. “closed” systems. Am J Physiol Regul Integr Comp Physiol 262: R725– R732, 1992. 12. Hill L and Bernard H. The influence of the force of gravity on the circulation. Part II. J Physiol (Lond) 21: 328–352, 1897. 13. Lillywh...

application to circulation of the giraffe head. Am J Physiol Regul Integr Comp Physiol 256: R567–R571, 1989. 11. Hicks JW and Badeer HS. Gravity and the circulation: “open” vs. “closed” systems. Am J Physiol Regul Integr Comp Physiol 262: R725– R732, 1992. 12. Hill L and Bernard H. The influence of the force of gravity on the circulation. Part II. J Physiol (Lond) 21: 328–352, 1897. 13. Lillywh...

application to circulation of the giraffe head. Am J Physiol Regul Integr Comp Physiol 256: R567–R571, 1989. 11. Hicks JW and Badeer HS. Gravity and the circulation: “open” vs. “closed” systems. Am J Physiol Regul Integr Comp Physiol 262: R725– R732, 1992. 12. Hill L and Bernard H. The influence of the force of gravity on the circulation. Part II. J Physiol (Lond) 21: 328–352, 1897. 13. Lillywh...