Melastoma malabathricum Linn. is a perennial traditional medicine plants that grows abundantly throughout Asian countries. In this study, M. malabathricum Linn. leaf hot water crude extract with anticoagulant activity was purified through solid phase extraction cartridge and examined for the bioactive chemical constituents on blood coagulation reaction. The SPE purified fractions were, respecti...

this study was conducted to determine the electrophoretic pattern of serum protein in goats infected withbabesia ovis. serum total protein was calculated and serum electrophoresis from 15 goats naturally infectedwith b. ovis as well as same number of healthy goats was performed. microscopic examination of giemsastained peripheral blood smears revealed b. ovis infection. the parasitological diag...

Telomeric repeat-containing RNA (TERRA) has been identified as a telomere-associated regulator of chromosome end protection. Here, we report that TERRA can also be found in extracellular fractions that stimulate innate immune signaling. We identified extracellular forms of TERRA in mouse tumor and embryonic brain tissue, as well as in human tissue culture cell lines using RNA in situ hybridizat...

CD44 is the major cell surface receptor for the extracellular matrix glycosaminoglycan hyaluronan and is implicated in a variety of biological events that include embryonic morphogenesis, lymphocyte recirculation, inflammation, and tumor metastasis. CD44 delivers activation signals to T lymphocytes, B lymphocytes, natural killer cells, polymorphonuclear leukocytes, and macrophages by stimulatin...

The lipid class compositions of subcellular fractions of SV40-transformed mouse fibroblasts derived from the logarithmic and stationary growth phase were compared. Cell populations of the stationary growth phase showed a relative decrease of the protein content and an increase of triglycerides and alkoxydiglycerides which could be located in the non-sedimenting fraction and in the nuclei and mi...

In etiolated pea (Pisum sativum L. cv. Alaska) shoots about 3% of the total extractable phytochrome was found in the mitochondrial fraction and about 4.5% in the microsomal fraction, while over 70% was soluble in the 105,000g supernatant. The value of Delta(DeltaA) per milligram of protein was significantly higher in the 105,000g supernatant than in these particulate fractions. The percentage c...

There are numerous reports in the literature on the separation from blood of leukocytes (e.g., 1-S) and of platelets (e.g., 9, 10). Existing procedures for the separation of the various cell types from the same sample of blood are rather elaborate and require relatively large amounts of blood (e.g., 11-13). In course of our study on the cellular transport of CNS drugs (e.g., 14-16), we became a...

BACKGROUND Ultrafine particles (UFP) may contribute to the cardiovascular effects of particulate air pollution, partly because of their relatively efficient alveolar deposition. OBJECTIVE In this study, we assessed associations between blood pressure and short-term exposure to air pollution in a population of schoolchildren. METHODS In 130 children (6-12 years of age), blood pressure was de...

Kidney, ureter, kidney artery, and kidney vein tissue were obtained from a single human transplant specimen. The donors erythrocyte blood group phenotype was AILe(a-b+). Total non-acid glycolipid fractions were isolated and individual glycolipid components were identified by immunostaining thin layer plates with a panel of monoclonal antibodies and by mass spectrometry of the permethylated and ...