AIMS To determine a concentration of ferritin below which the possibility of iron deficiency should be considered in elderly patients. METHODS Consecutive new referrals to a geriatric unit (n = 472) were studied prospectively. Full blood count, ferritin, serum vitamin B12 and red cell folate were measured for all patients. A blood film was assessed independently by three haematologists for fe...

Determination of the reticulocyte hemoglobin content (CHr) provides an early measure of functional iron deficiency because reticulocytes are the earliest erythrocytes released into blood and circulate for only 1 to 2 days. The CHr in 78 patients undergoing bone marrow examination was measured to assess its clinical utility for the diagnosis of iron deficiency. Twenty-eight patients were iron de...

NEW DRUGS Ferriprox Reduces Excess Iron Deferiprone (Ferriprox, Apo-Pharma, Inc.) has been approved to treat iron overload resulting from blood transfusions in patients with thalassemia who have responded inadequately to previous chelation therapy. Thalassemia is a genetic blood disorder that causes anemia. Patients with thalassemia have excess iron levels from frequent blood transfusions, a se...

BACKGROUND Despite several, well-documented pro-healthy effects of regular physical training, its influence on body iron stores in elderly people remains unknown. At the same time, body iron accumulation is associated with high risk of different morbidities. PURPOSE We hypothesized that Nordic Walking training would result in pro-healthy changes in an elderly group of subjects by reducing bod...

Background: Iron deficiency anemia (IDA) is the most common cause of anemia worldwide. It is widely accepted that chronic occult blood loss from the gastrointestinal tract is a major cause of IDA. This study aimed to evaluate small intestinal lesions in patients with unexplained iron deficiency anemia, with or without fecal occult blood by enteroscopy and to elucidate the pathologic nature of s...

OBJECTIVE To study iron exchange irregularities in experimental animals and patients with glial brain tumors to ascertain the role of the 'iron component' in glial brain tumor pathogenesis. SUBJECT AND METHODS A suspension of A.101.08 tumor cells was implanted in the cortex of the left-brain hemisphere of rats to model experimentally induced glial brain tumor. At 7 or 14 days after implantati...

BACKGROUND Iron plays an essential role in various tissue functions, and hence the reliable assessment of iron nutrition status of preterm infants appears to be mandatory. OBJECTIVES To summarize available data on cord blood concentrations of iron status parameters as surrogate reference ranges for preterm infants until term-equivalent age. METHODS Review of the literature searching PubMed ...

The prevalence of anemia in pregnancy varies considerably because of the differences in social conditions, lifestyles, and health seeking behaviors across different cultures. Anemia affects all pregnant women in the world—52 % in developing countries compared with 23 % in the developed world. It is one of the most prevalent nutritional deficiency problems affecting pregnant females. Iron defici...

BACKGROUND Iron deficiency without anemia is related to adverse symptoms that can be relieved by supplementation. Since a blood donation can induce such an iron deficiency, we investigated the clinical impact of iron treatment after a blood donation. METHODS One week after donation, we randomly assigned 154 female donors with iron deficiency without anemia, aged below 50 years, to a four-week...

objective febrile convulsions are prevalent in children aged between 9 months and 5 years, with an incidence of 2-5%. on the other hand, iron deficiency anemia is the most common hematologic disease of infancy and childhood with a period of incidence that coincides with the time of developing febrile convulsions. therefore, it is hypothesized that there is a possible association between these c...