There are many reports for involvement of ATP-sensitive potassium channels in pancreatic, cardiac and vascular smooth muscle cells. This study examined the effect of single doses of K+ channel openers diazoxide, minoxidil and K+ channel blockers chlorpropamide, glibenclamide on serum concentration of aldosterone in male rats. Blood samples were obtained 60 minutes after drug treatment and serum...

The amino acid sequence of the M-protein for multiple myeloma is unique compared to polyclonal antibodies in patients’ blood. This uniqueness exploited develop an ultrasensitive detection method utilizing mass spectrometry (MS). involves de novo sequencing full-length M-protein, and a targeted MS/MS assay detect quantify serum samples. Healthy control spiked with NISTmAb serial samples from MM ...

Abstract Background Widespread investigation of these biomarkers in large population studies has been hampered as several blood cognitive impairment need the to be processed immediately into plasma/serum. We evaluated stability delayed processing using an ultra‐sensitive assay. Method collected from 20 volunteers (0 hours), and after a delay 24 hours 48 obtain serum. In addition, we also five h...

Background: Beta-thalassemia major is a type of inherited blood disease that results in variable outcomes such as severe anemia due to haemoglobin chains. Recurrent and lifelong blood transfusions as a treatment in beta-thalassemia major disease lead to iron deposition in various organs and cause the failure of multiple organs. Failure of affected organs leads to Body mass index (BMI) abnormali...

Chub mackerel (Scomber japonicus Houttuyn, 1782) were obtained from the commercial fishermen in Çanakkale, Turkey, July, 2017. We examined a total of 40 fish (20 non-infested and 20 infested) assessed biometric indices, haematological parameters serum biochemical variables. The hepatosomatic index gonadosomatic infested chub lower than those fish. Blood haematocrit ratio haemoglobin concentrati...