Tianma is a traditional Chinese medicine (TCM) often used for the treatment of hypertension and heart diseases. To elucidate the function of tianma at the molecular level, we investigated the effect of tianma on vascular functions and aortic protein metabolism. We found that long-term treatment with tianma (~2.5g/kg/day for three months) in one-year-old rats could enhance acetylcholine (ACh)-in...

Measurements of retinal blood vessel morphology have been shown to be related to the risk of cardiovascular diseases. The wrong identification of vessels may result in a large variation of these measurements, leading to a wrong clinical diagnosis In this paper, address of the problem identifying true vessels as a post processing step to vascular structure classification. These model classified ...

................................................................................................................................... 7 REVIEW OF THE LITERATURE ............................................................................................ 8 The formation of blood and lymphatic vessel networks during embryonic development .................... 8 Vasculogenesis and angiogenesis..........

The flow-stimulated intracellular Ca(2+) concentration ([Ca(2+)]i) rise in endothelial cells is an important early event leading to flow-induced blood vessel dilation. Transient receptor potential vanilloid subtype 4 (TRPV4), a Ca(2+)-permeable cation channel, facilitates the flow-stimulated [Ca(2+)]i rise. To determine whether TRPV4 is involved in age-related flow-induced blood vessel dilation...

Copper (Cu) is a vital trace element for maintaining human health. Current evidence suggests that genes responsible regulating copper influx and detoxification help preserve its homeostasis. Adequate Cu levels sustain normal cardiac blood vessel activity by mitochondrial function. Cuproptosis, unlike other forms of cell death, characterized alterations in enzymes. Therapeutics targeting cupropt...

The accurate analysis of Coronary angiographic images plays an important role in diagnosing arterial diseases. All angiograms suffer from varying background, consisting of heart tissues, which harden accurate detection of vessels. Therefore removing background is one of the important steps which have essential effect on improving performance of subsequent steps of vessel detection algorithm, es...

A 54-year-old man presented with nonprogressive dysarthria due to isolated right hypoglossal nerve (HN) palsy. The cranial MRI reveals an ectatic right vertebral artery impinging on the cisternal segment of HN (figure). The hypoglossal-vertebral entrapment syndrome1 occurs as the hypoglossal rootlets converge directly over the distorted vessel with resultant mechanical compression and direct ne...

BACKGROUND Blood vessel mechanics has traditionally been of interest to researchers and clinicians. Changes in mechanical properties of arteries have been associated with various diseases. OBJECTIVE To provide a comprehensive review directed towards understanding the basic biomechanical properties of cerebral arteries under normal and diseased conditions. METHODS Literature review supplemen...

BACKGROUND The morphological changes of the retinal blood vessels in retinal images are important indicators for diseases like diabetes, hypertension and glaucoma. Thus the accurate segmentation of blood vessel is of diagnostic value. METHODS In this paper, we present a novel method to segment retinal blood vessels to overcome the variations in contrast of large and thin vessels. This method ...

Blood microparticles are vesicular structures with a diameter of 100 to 1000 nm that are present in the blood of normal subjects and in patients with various diseases. These microparticles are derived from cells that circulate in the blood and cells associated with the blood vessel wall. Microparticle membranes retain the protein receptors of their parent cells and may retain RNAs and other cyt...