BACKGROUND High mobility group box 1 (HMGB1) is a late mediator of systemic inflammation. Extracellular HMGB1 play a central pathogenic role in critical illness. The purpose of the study was to investigate the association between plasma HMGB1 concentrations and the risk of poor outcomes in patients with severe blunt chest trauma. METHODS The plasma concentrations of HMGB1 in patients with sev...

purpose : this study was performed to compare complications and clinical course of microscopic and macroscopic hyphema resulting from blunt ocular trauma methods : in a prospective observational case series during the period 21 march 2010 to 20 march 2011 all referred patient with traumatic hyphema to ophthalmic emergency ward of ahvaz, main city of southwest of iran that met inclusion criteria...

BACKGROUND Adrenal gland trauma is a rare condition that typically stems from blunt force trauma, and is associated with multiple organ injuries. Alternatively, isolated adrenal gland trauma is extremely rare, accounting for only 1.5 to 4% of all adrenal trauma cases. While isolated adrenal trauma is a mostly self-limiting condition, it is potentially life-threatening, representing a significan...

BACKGROUND Uncontrolled bleeding is a leading cause of death in trauma. Two randomized, placebo-controlled, double-blind trials (one in blunt trauma and one in penetrating trauma) were conducted simultaneously to evaluate the efficacy and safety of recombinant factor VIIa (rFVIIa) as adjunctive therapy for control of bleeding in patients with severe blunt or penetrating trauma. METHODS Severe...

Blunt vascular trauma of the lower extremities brings about a high amputation rate, because other organ injuries disturb revascularization. We experienced a case of a superficial femoral artery occlusion caused by blunt trauma. The patient also had a femoral bone fracture and a large skin defect with deep muscular injuries of the thigh. We performed a femoropopliteal (FP) bypass using a sapheno...

introduction lung herniation following blunt chest trauma is extremely rare and only a few hundred cases of this pathology have been reported in the english language medical literature. this type of lung hernia is divided into intercostal, parasternal, or supraclavicular subtypes based on the exact location of the chest wall defect. traumatic intercostal lung hernia is even more uncommon. delay...

BACKGROUND Our objective was to assess the cost-effectiveness of emergency department thoracotomy (EDT) performed on both penetrating and blunt trauma victims, using both published survival and outcome data and previously unaccounted for data on the cost of occupational exposure. METHODS Cost-utility analysis was performed using decision-analytic models constructed for both penetrating and bl...

47 January 2015, Vol. 105, No. 1 Trauma is a leading cause of death in the developing world, and represents a major burden of disease in South Africa (SA).[1,2] Children are disproportionately affected.[3] Blunt trauma secondary to motor vehicle collisions (MVCs) contributes to the majority of admissions to trauma centres.[4] Significant blunt thoracic trauma in both adults and children require...

Blunt injury to the chest can affect any one or all components of the chest wall and thoracic cavity. The clinical presentation of patients with blunt chest trauma varies widely and ranges from minor reports of pain to florid shock. Traumatic tricuspid valve regurgitation is a rare cardiovascular complication of blunt chest trauma. Tricuspid valve regurgitation is usually begotten by disorders ...