نتایج جستجو برای: bmp7

تعداد نتایج: 600  

2010
Nobuhiro Kamiya Donald J. Lucas M. Joiner Steve A. Goldstein Yuji Mishina

Bone morphogenetic proteins (BMPs) are known as ectopic bone inducers. The FDA approved BMPs (BMP2 and BMP7) for clinical use. However, direct effects of BMPs on endogenous bone metabolism are not yet well known. We recently reported that loss of BMPRIA (ALK3), a potent receptor for BMP2 and BMP4, in osteoblasts unexpectedly increased endogenous bone mass during embryonic and adult stages (ref ...

Journal: :Genetics and molecular research : GMR 2014
P Lu X Feng J S Zhou X B Liu Q X Chen M Li

Bone morphological protein7 (BMP7), a member of the transforming growth factor-β (TGF-β) family, was first identified because of its ability to induce ectopic chondro-osteogenesis in vivo. It also plays a crucial role in the growth, development, and physiological functioning of the reproductive system. Among intra-ovarian growth factors, many studies have shown that BMP7 plays a pivotal role in...

Journal: :Cellular Physiology and Biochemistry 2015

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