Methods Since the beginning of 2012 four cases who have been presented with sternal tumors and one with post cardiac surgery infection were selected for chest wall reconstruction with bone allograft. One patient had missed diagnosis as a case of breast tumor with final diagnosis of synovial cell sarcoma. The other one had upper sternum bulging. Truecut biopsy was suggestive of myxoid tumor. Thi...

Cortical onlay strut allografting is emerging as a very attractive option for periprosthetic femoral fractures around stable implants. The cortical struts essentially represent biologic bone plates. In addition to conferring mechanical stability they may enhance fracture healing and can potentially increase bone stock. If appropriately selected and prepared, cortical struts can be customized to...

To improve the safe use of allograft bone, decellularization techniques may be utilized to produce acellular scaffolds. Such scaffolds should retain their innate biological and biomechanical capacity and support mesenchymal stem cell (MSC) osteogenic differentiation. However, as allograft bone is derived from a wide age-range, this study aimed to determine whether donor age impacts on the abili...

Anterior cruciate ligament (ACL) injury is one of the most common ligament injuries involving the knee, especially in the young, athletic population. Bone-patellar tendon-bone (BPTB) and semitendinous gracilis autografts are some of the procedures used for ACL reconstruction. However, these procedures are associated with significant problems, including quadriceps weakness, patellofemoral pain, ...

Controversy exists regarding the most predictable salvage for failed total ankle replacement. Revision total ankle replacement with soft-tissue release/reconstruction or explantation with tibio-talo-calcaneal arthrodesis with bulk structural allograft are the most commonly performed approaches. Tibio-talo-calcaneal arthrodesis with bulk structural allograft has a high complication rate; however...

Anterior glenoid bone loss is present in nearly all cases of recurrent anterior glenohumeral instability. Treating glenoid bone loss in the setting of recurrent instability is challenging, and often, soft tissue stabilization procedures in isolation are inadequate. The nonanatomic, incongruous joint resulting from most bony augmentation procedures has motivated investigators to find an alternat...

With patients undergoing first time 1st metatarsophalangeal joint arthrodesis using graft material when it was required to fill cystic bone voids, we retrospectively compared the time to fusion (clinical and radiographic), and non-union rate between the patient’s own bone autograft (n = 62) versus a mesenchymal stem cell impregnated allograft group (n = 51). A third control group (n = 52) was i...

STUDY DESIGN Systematic review. OBJECTIVE To compare the effectiveness and safety between iliac crest bone graft (ICBG), non-ICBG autologous bone, and allograft in cervical spine fusion. To avoid problems at the donor site, various allograft materials have been used as a substitute for autograft. However, there are still questions as to the comparative effectiveness and safety of cadaver allo...

Why is the risk of disease transmission with bone allograft an important topic? Approximately 1 million bone allografts are implanted every year in the United States. Although safety measures to prevent disease transmission have improved significantly over the past 2 decades, infectious complications remain a relevant concern. During informed consent, patients invariably take pause at the prosp...