Abstract Although multiple studies have investigated the mesenchymal stem and progenitor cells (MSCs) that give rise to mature bone marrow, high heterogeneity in their morphologies properties causes difficulties molecular separation of distinct populations. In this study, by taking advantage resolution single cell transcriptome, we analyzed Sca-1 PDGFR-? fraction mouse marrow tissue. The transc...

stem cells are of great interest for regenerating disturbed tissues and organs. these cells are commonly isolated from the bone marrow, but there has been interest in other tissues in the recent years. in this study, we evaluated the possibility of isolation of stem cells from oral connective tissue and investigated their characteristics.in this experimental study, sampling from the bone marrow...

Human mesenchymal stem cells are thought to be multipotent cells, which are present in adult marrow, that can replicate as undifferentiated cells and that have the potential to differentiate to lineages of mesenchymal tissues, including bone, cartilage, fat, tendon, muscle, and marrow stroma. Cells that have the characteristics of human mesenchymal stem cells were isolated from marrow aspirates...

Introduction: Bone marrow (BM) is a known source of mesenchymal stem cells (MSCs) that are used for cell therapy. This study attempts to identify if the Wharton’s Jelly (WJ) is a suitable substitute for BM as a source for MSCs. Materials and Methods: A population of human WJ and BM stem cells were isolated and incubated with fluorescein conjugated antibodies for five specific MSC markers....

PURPOSE The aim of this study is to compare the gene expression profile in mesenchymal stem cells derived from dental tissues and bone marrow for characterization of dental stem cells. METHODS We employed GeneChip analysis to the expression levels of approximately 32,321 kinds of transcripts in 5 samples of bone-marrow-derived mesenchymal stem cells (BMSCs) (n=1), periodontal ligament stem ce...

INTRODUCTION Mesenchymal stem cells (MSCs) are defined as cells that can differentiate into multiple mesenchymal lineage cells. MSCs were obtained from various sources; bone marrow, umbilical cord blood, adipose tissue and synovium etc. It has been reported that MSCs isolated from the bone marrow showed variation in size, morphology and level of alkaline phosphatase activity among clones isolat...

Disorders of the esophagus could include various conditions such as inflammation, stricture or esophageal-phase dysphagia. Management these disorders is rapidly developing, which includes conservative, surgical and modern techniques use stem cells. Stem cells are characterized have not differentiated, able to multiply differentiate into multiple organ cells, has ability self-renewal vital in di...

OBJECTIVE Although mesenchymal stem/stromal cells represent a promising therapeutic strategy for acute respiratory distress syndrome, clinical translation faces challenges, including scarcity of bone marrow donors, and reliance on bovine serum during mesenchymal stem/stromal cell proliferation. We wished to compare mesenchymal stem/stromal cells from human umbilical cord, grown in xeno-free con...

Sixty-nine patients who underwent primary percutaneous coronary intervention within 12 hours after onset of acute myocardial infarction were randomized to receive intracoronary injection of autologous bone marrow mesenchymal stem cell or standard saline. Several imagining techniques demonstrated that bone marrow mesenchymal stem cells significantly improved left ventricular function.