BACKGROUND A two-year, community-based, group-randomized trial to promote bone mass gains among 9-11 year-old girls through increased intake of calcium-rich foods and weight-bearing physical activity was evaluated. METHODS Following baseline data collection, 30 5th-grade Girl Scout troops were randomized to a two-year behavioral intervention program or to a no-treatment control group. Evaluat...

The effects of chronic dietary acid loads on shifts in bone mineral reserves and physiological concentrations of cations and anions in extracellular fluids were assessed in growing swine. Four trials were conducted with a total of 38 (8.16 +/- 0.30 kg, mean +/- SEM) Large White x Landrace x Duroc pigs randomly assigned to one of three dietary treatments. Semipurified diets, fed for 13 to 17 d, ...

PURPOSE Osteoporosis occurs in both women and men, but most of what we know about the condition comes from studies in females. The present study examined bone structure and function over an 18-month period in male C57BL/6 mice maintained on either a rodent chow diet (AIN76A) or a high-fat, Western-style diet (HFWD). Effects of mineral supplementation were assessed in both diets. METHODS Trabe...

Bone mineral content (BMC) and bone mineral density (BMD) measurements were made by dual-energy x-ray absorptiometry (DEXA) in 112 healthy 12-yr-old white girls for the purposes of: (1) establishing reference data on total-body mineral content of 12-yr-old girls and (2) comparing the lumbar spinal bone density values from a dedicated scan with the lumbar region of interest bone density values f...

BACKGROUND We aimed to describe the longitudinal changes in bone mineral content and influencing factors, in children with cystic fibrosis (CF). METHODS One hundred children (50 females) had dual X-ray absorptiometry (DXA) performed. Of these, 48 and 24 children had two to three scans, respectively over 10 years of follow-up. DXA data were expressed as lumbar spine bone mineral content standa...

A meta-analysis of adult exercise studies and an infant activity trial show a possible interaction between physical activity and calcium intake on bone. This randomized trial of activity and calcium supplementation was conducted in 239 children aged 3-5 years (178 completed). Children were randomized to participate in either gross motor or fine motor activities for 30 minutes/day, 5 days per we...