The ideal bone substitute biomaterial should have mechanical properties similar to that of human bone tissue. Hydroxyapatite (HA) alone suffers from low fracture toughness, and most polymers alone lack sufficient stiffness and strength, limiting applications in load-bearing implants. Synthetic HA whisker reinforced polymer biocomposites provide a means to overcome these deficiencies (Roeder, et...

The development of an osteogenic bone graft substitute has important practical and cost implications in many branches of medicine where bone regeneration is required. Previous in vitro and small animal (murine) in vivo studies highlighted a porous hydroxyapatite/poly (DL-lactic acid) composite scaffold in combination with skeletal stem cells (SSCs) as a potential bone graft substitute candidate...

The aim of this narrative review is to describe treatment options for the posterior regions of the mandible and the maxilla, comparing short implants vs. longer implants in an augmented bone. The dental literature was screened for treatment options enabling the placement of dental implants in posterior sites with a reduced vertical bone height in the maxilla and the mandible. Short dental impla...

Background and Aim: Several reports have been published on the successful application of various bone substitute materials (BSM). Appropriate physiologic and histologic characteristics and reactions of these materials against host cells are critically important. In this study, the biocompatibility of a new bone substitute material has been evaluated. Methods and Materials: In this experime...

BACKGROUND In implant dentistry, bone substitute materials and barrier membranes are used in different treatments including guided bone regeneration (GBR), socket preservation, alveolar ridge augmentation, maxillary sinus elevation, and filling bony defects around the inserted dental implant. One of the most important factors in prognosis of treatments using these materials is the growth of new...

PURPOSE In THA a sufficient primary implant stability is the precondition for successful secondary stability. Industrial foams of different densities have been used for primary stability investigations. The aim of this study was to analyse and compare the insertion behaviour of threaded and press-fit cups in vivo and ex vivo using bone substitutes with various densities. METHODS Two threaded ...

INTRODUCTION: Many bone graft substitutes have become available to assist in increasing healing rates and decrease donor site morbidity resulting from orthopaedic procedures. Calcium sulfate is a widely used bone graft substitute, and is now available as a bone void filler as well as in pellets. We wished to examine: 1. The effect of a solid calcium sulphate cylinder in an intercalary defect in...

Objectives There is strong current interest in the use of biodegradable scaffolds in combination with bone growth factors as a valuable alternative to the current gold standard autograft in spinal fusion surgery (Yong et al. 2013). Here we report on 6vs 12month data set evaluating the longitudinal performance of a CaP coated polycaprolactone (PCL) scaffold loaded with recombinant human bone mor...