Affective instability and self-injurious behavior are important features of Borderline Personality Disorder. Whereas affective instability may be caused by a pattern of limbic hyperreactivity paired with dysfunctional prefrontal regulation mechanisms, painful stimulation was found to reduce affective arousal at the neural level, possibly underlying the soothing effect of pain in BPD.We used psy...

BACKGROUND Patients with borderline personality disorder often are found and treated in psychiatric settings following episodes of self-mutilation, such as wrist-slashing. Family physicians care for many patients with borderline personality disorder, but in primary care settings wrist-slashing or other physical mutilation is a less common presenting problem. Frequently these patients complain o...

OBJECTIVE The purpose of this study was to compare the axis II comorbidity of 202 patients whose borderline personality disorder (BPD) remitted over 6 years of prospective follow-up to that of 88 whose BPD never remitted. METHOD The axis II comorbidity of 290 patients meeting both DIB-R and DSM-III-R criteria for BPD was assessed at baseline using a semistructured interview of demonstrated re...

BACKGROUND There are still many unanswered questions about psychological and social factors that may affect the development and treatment of borderline personality disorder (BPD). Religion/spirituality (R/S) is a factor that could influence the lives of people with BPD. OBJECTIVE The aim of this study was to evaluate the relationship between religiosity, religious attendance and borderline pe...

OBJECTIVE To describe the concept of mentalization, and its application in understanding the development of psychopathology in patients with borderline personality disorder; to give an account of the main features of mentalization-based treatment; to summarise the evidence supporting its effectiveness. DISCUSSION Mentalization is a predominantly preconscious mental activity that enables the i...

als with comorbid PTSD and borderline personality disorder had greater odds of lifetime suicide attempt compared to individuals with either condition alone (4). We have shown that individuals with co-occurring PTSD and borderline personality disorder have higher odds of having a suicide attempt than either disorder alone (3, 4). These findings are in contrast to the findings of Harned and col-l...

OBJECTIVE The authors sought to evaluate the clinical efficacy of dialectical behavior therapy compared with general psychiatric management, including a combination of psychodynamically informed therapy and symptom-targeted medication management derived from specific recommendations in APA guidelines for borderline personality disorder. METHOD This was a single-blind trial in which 180 patien...

BACKGROUND Central to most theories of borderline personality disorder (BPD) is the notion that the family environment interacts with genetically-based vulnerabilities to influence the development of BPD, with particular attention given to risk conferred by conflictual familial relations. However, the extent to which family conflict may relate to the development of BPD via related interpersonal...

A randomized, controlled study was carried out to assess the effect of a series of 10 sessions of high-frequency rTMS to the right DLPFC in 10 Borderline Personality Disorder patients. Patients in the rTMS group showed improvements in anger, affective instability (Borderline Personality Disorder Severity Index) and planning (Tower Of London). Two smoking cessations were observed.

Citation: Krauch M, Ueltzhöffer K, Brunner R, Kaess M, Hensel S, Herpertz SC and Bertsch K (2018) Heightened Salience of Anger and Aggression in Female Adolescents With Borderline Personality Disorder—A Script-Based fMRI Study. Front. Behav. Neurosci. 12:57. doi: 10.3389/fnbeh.2018.00057 Heightened Salience of Anger and Aggression in Female Adolescents With Borderline Personality Disorder—A Scr...