Aim: The aim of the present study was to design and evaluate solid lipid nanoparticles Asenapine maleate (<2% bioavailability) enhance its oral bioavailability surface modification for brain targeting.
 Methods: A modified solvent injection method used produce loaded nanoparticles. RSM 3-factor, 3-level Box-Behnken applied effect three independent variables, concentrations (A), drug (B)...

the main objective of the present study is to investigate the feasibility of using carboxymethyl chitosan magnetic nanoparticles (ccmn) for the adsorption of cd2+. the study also reports important parameters, which affect the adsorption process, i.e., ph, adsorbent dose, contact time and concentration of cd2+, using box-behnken designs. firstly, functional carboxymethyl chitosan magnetic nanopa...