OBJECTIVE This study evaluated the possibility of accelerated gadolinium accumulation in irradiated brain parenchyma where the blood-brain barrier was weakened. METHODS From January 2010 to June 2015, 44 patients with supratentorial glioblastoma were retrospectively identified who underwent pre- and post-radiation brain MR imaging, including R1 mapping. The mean dose of administered gadobutro...

PURPOSE This study was designed to determine the influencing factors and clinical course of pathologically proven cases of radiation-induced brain injury (RIBI). MATERIALS AND METHODS The pathologic records of twelve patients were reviewed; these patients underwent surgery following radiotherapy due to disease progression found by follow-up imaging. However, they were finally diagnosed with R...

Abstract INTRODUCTION Patients with multiple sclerosis (MS) may be at higher risk of brain tumors (Khalil 2012, London 2020, etc.). However, MS patients have been reported to adverse effects from radiotherapy, a mainstay CNS treatment. In the last ten years, radiation techniques improved. We submit case report an patient demyelinating lesions shortly after therapy for astrocytoma and review lit...

The factors affecting the prognosis of 85 patients with brain metastases from August 1973 to August 1992 were analyzed. The following specific factors were reviewed; (1) patient age, (2) primary site, (3) disease free interval, (4) presence or absence of disseminated disease, (5) initial neurological symptoms (focal signs or IICP signs), (6) single or multiple metastases, and (7) treatment (sur...

Brain metastases are the most common intracranial malignancy, accounting for significant morbidity and mortality in oncology patients. The current treatment paradigm for brain metastasis depends on the patient's overall health status, the primary tumor pathology, and the number and location of brain lesions. Herein, we review the modern management options for these tumors, including surgical re...

BACKGROUND This review evaluates the effectiveness and safety of elemene injection combined radiotherapy in the treatment of lung cancer with brain metastases. METHODS A systematic literature research was conducted from EMBASE, Cochrane Library, PubMed, Chinese biomedical database, Chinese scientific journal database, China knowledge resource integrated database, and WanFang Database from est...