Sarcopenia is the decline of muscle mass and strength with age. Evidence suggests that oxidative stress and molecular inflammation play important roles in age-related muscle atrophy. The two factors may interfere with the balance between protein synthesis and breakdown, cause mitochondrial dysfunction, and induce apoptosis. The purpose of this review is to discuss some of the major signaling pa...

Our knowledge of protein synthesis in vitro has increased appreciably over the last few years-by contrast the problems of protein turnover are little understood. Since the level of protein in living tissues is controlled by the process of turnover, several techniques for measuring this have been devised. This paper is mainly concerned with those methods which are used to assess turnover in whol...

At parturition, breakdown of extracellular matrix in the fetal membranes may play a part in the rupture of the membranes and in the aetiology of premature rupture, in addition to having a regulatory role in the cell-cell interactions and signalling at the feto-maternal interface to stimulate myometrial contractility. The matrix metalloproteinases (MMPs) are important enzymes for the breakdown o...

Onset of intracellular acidosis during muscular exercise has been generally attributed to activation or hyperactivation of nonoxidative ATP production but has not been analyzed quantitatively in terms of H(+) balance, i.e., production and removal mechanisms. To address this issue, we have analyzed the relation of intracellular acidosis to H(+) balance during exercise bouts in seven healthy subj...

the concept of imagery is to make an image of successful movement skill or a relaxing image in mind with no body training and external experience. the aim of the present study was to compare the effect of traditional and pettlep mental imagery methods on static and dynamic balance. the statistical population consisted of all female university of tehran students who had general physical educatio...

This study explored if a combined supplementation of GH and IGF-1 had an additive effect on whole body nitrogen economy, energy, substrate and skeletal muscle metabolism following surgical trauma. Patients were randomized to controls (C; n = 10), to GH (0.15 IU/kg/injection) (GH; n = 7) or GH combined with IGF-1 (40 mug/kg/injection) subcutaneously twice a day (GH-IGF-1; n = 9) together with st...

the purpose of present study was to determine the effect of different levels of balance task difficulty and visual feedback on balance in elderly women. fourteen healthy elderly women (mean age 57/65 yr) were selected voluntarily. participants were asked to stand still on a stability platform under each of two conditions (with visual feedback and without visual feedback) in three levels of diff...

This paper provides the first systematic attempt to investigate the legislative impact of the Scottish Parliament on Executive legislation by analysing the fate of all amendments to Executive bills from the Parliament’s first session (1999-2003). Initial findings on the success of bill amendments show that the balance of power inclines strongly in favour of ministers. However, when we account f...

Theoretical analysis suggests that enlargement of a voting body may affect the balance of power between the original members even if their number of votes and the decision rule remain constant. Some of the existing voters may actually gain, a phenomenon known as the paradox of newmembers.We test for this effect using laboratory experiments. Participants propose and vote on how to divide a budge...