نتایج جستجو برای: bsmi polymorphism and vitamin d receptor gene

تعداد نتایج: 17155683  

Journal: :Mutagenesis 2012
Natalie Many Felix Stickel Johannes Schmitt Bruno Stieger Michael Soyka Pascal Frei Oliver Götze Beat Müllhaupt Andreas Geier

Increased serum bile salt levels have been associated to a single-nucleotide polymorphism in the bile salt export pump (BSEP; ABCB11) in several acquired cholestatic liver diseases but there is little evidence in alcoholic liver disease (ALD). Furthermore, a crosstalk between vitamin D and bile acid synthesis has recently been discovered. Whether this crosstalk has an influence on the course of...

Journal: :Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2009
Lina Chen George Davey Smith David M Evans Angela Cox Debbie A Lawlor Jenny Donovan Wei Yuan Ian N M Day Richard M Martin Athene Lane Santi Rodriguez Michael Davis Luisa Zuccolo Simon M Collin Freddie Hamdy David Neal Sarah J Lewis

Low levels of plasma vitamin D have been implicated as a possible risk factor for both prostate cancer incidence and advanced disease, and recent phase II trials suggest that vitamin D supplementation might delay progression of prostate cancer. Common polymorphisms in the vitamin D receptor (VDR) are associated with VDR activity and are therefore potentially useful proxies for assessing whether...

Journal: :medical journal of islamic republic of iran 0
zahra mohammadi osteoporosis research center, endocrinology and metabolism clinical sciences institute, tehran university of medical sciences, tehran, iran.سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (tehran university of medical sciences)سازمان های دیگر: osteoporosis research center endocrinology and metabolism clinical sciences institute abbasali keshtkar osteoporosis research center, endocrinology and metabolism clinical sciences institute, tehran university of medical sciences, tehran, iran.سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (tehran university of medical sciences)سازمان های دیگر: osteoporosis research center endocrinology and metabolism clinical sciences institute, fateme fayyazbakhsh biomedical engineering department, maziar university, rouyan, iran.سازمان اصلی تایید شده: موسسه آموزش عالی مازیار رویان mehdi ebrahimi osteoporosis research center, endocrinology and metabolism clinical sciences institute, tehran university of medical sciences, tehran, iran.سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (tehran university of medical sciences)سازمان های دیگر: osteoporosis research center

background: osteoporosis, or porous bone, is a disease characterized by low bone mass density (bmd) and structural deterioration of bone tissue, leading to bone fragility and increased risk of hip, spine, and wrist fractures. there are numerous risk factors for osteoporosis. while many of these factors are non-genetic in nature, there is a definite genetic component responsible for this conditi...

Arghavan Azizpour, Azadeh Goodarzi, Ghazaleh Zarrinrad Ifa Etesami Maede Rayati Damavandi Mohammad Keramatipour Nafiseh Esmaili Narges Ghandi, Somayeh Ahmadloo zeinab Aryanian,

Background: Pemphigus vulgaris (PV) is an autoimmune bullous disease of the skin and mucous membranes caused by activation and proliferation of T cells, production of Th2 cytokine profile and pathogenic antibodies. Vitamin D is a probable immunodeviator to Th2, which its actions are mediated through the vitamin D receptor (VDR). FokI is the only single nucleot...

Journal: :European journal of endocrinology 2004
Elin Grundberg Helena Brändström Eva L Ribom Osten Ljunggren Hans Mallmin Andreas Kindmark

OBJECTIVE Bone mineral density (BMD) is under strong genetic control and a number of candidate genes have been associated with BMD. Both muscle strength and body weight are considered to be important predictors of BMD but far less is known about the genes affecting muscle strength and fat mass. The purpose of this study was to investigate the poly adenosine (A) repeat and the BsmI SNP in the vi...

Journal: : 2023

Introduction . Vitamin D deficiency may be a natural predictor of the onset coronary heart disease (CHD) and myocardial infarction (MI) at young age. The results studies various variants association vitamin receptor (VDR) gene with risk CHD are contradictory, which leads to study genetic VDR as predictors age 45 years younger in Russian population. objective was determine distribution TaqI , Bs...

Journal: :Journal of biostatistics and epidemiology 2022

Introduction: An important part of preventing major common diseases is identifying genetic factors that contribute to their occurrence. For the first time in our knowledge, we investigated association between five polymorphisms vitamin D receptor (VDR) gene (ApaI, BsmI, FokI, EcoRV, and TaqI) low bone density/osteopenia/osteoporosis individuals with type 2 diabetes using classification regressi...

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