The present research article relates to the discovery of the novel drugs based on Zonisamide to treatment of autism disease. In first step, the electronic properties, reactivity and stability of the said compound are discussed. To attain these properties, the said molecular structure is optimized using B3LYP/6-311++G(d,p) level of theory at room temperature. The frontier molecular orbitals (FMO...

We describe an object classification method that can learn from a single training example. In this method, a novel class is characterized by its similarity to a number of previously learned, familiar classes. We demonstrate that this similarity is well-preserved across different class instances. As a result, it generalizes well to new instances of the novel class. A simple comparison of the sim...

the solutions of mathematical models for the estimation of the kinetic, and biokinetic parameters of naphthalene, anthracene and pyrene during degradation in surface and subsurface soils are presented in this work. the models were developed using the twin concepts of rate-determining step and steady-state approximation method. they described the biodegradation of single and a mixture of polycy...

Background: CDKN2A, encoding two important tumor suppressor proteins p16 and p14, is a tumor suppressor gene. Mutations in this gene and subsequently the defect in p16 and p14 proteins lead to the downregulation of RB1/p53 and cancer malignancy. To identify the structural and functional effects of mutations, various powerful bioinformatics tools are available. The aim of this study is the ident...

Abstract Background The effect of heat stress on livestock production is a worldwide issue. Animal performance influenced by exposure to harsh environmental conditions potentially causing genotype-by-environment interactions (G × E), especially in highproducing animals. In this context, the main objectives study were (1) detect time periods which heifer fertility traits are more sensitive high ...