insights from the randomized TAXUS II trial. Circulation 2005;111:900–905. 27. Wieneke H, Dirsch O, Sawitowski T, Gu YL, Brauer H, Dahmen U, Fischer A, Wnendt S, Erbel R. Synergistic effects of a novel nanoporous stent coating and tacrolimus on intima proliferation in rabbits. Catheter Cardiovasc Interv 2003;60: 399–407. 28. Kollum M, Farb A, Schreiber R, Terfera K, Arab A, Geist A, Haberstroh ...

CCD UBV RI photometry is presented for type Ia supernova 2004fu in NGC 6949. The light and colour curves are typical for this class of objects, absolute magnitude at maximum and decline rate are in agreement with the relationship between these parameters, established for SNe Ia. SN 2004fu was discovered by Arbour (2004) on unfiltered CCD images taken with a 0.3-m Schmidt-Cassegrain reflector on...

Cultured cell lines LL, B1 6, C26, and C38 establ ished from mouse solid tumors of Lewis lung carcinoma, B1 6 melanoma, and colon adenocarc inomas 26 and 38, respectively, showed inherent ly dif ferent resistance to vincrist ine (VCR) in vitro. The inherent resistance to VCR of these cell lines was related to the abil ity of the cells to accumulate VCR. Verapamil , a calcium antagonist with cor...

Oropharyngeal candidiasis (OPC) is the most common opportunistic infection in HIV-infected patients and is considered a clinical marker of disease progression (3). A reduction in the incidence of OPC and some cases of resolution of refractory mucosal candidiasis following introduction of HIV protease inhibitor (HIV-PI) therapy have recently been reported (6, 10, 11). To switch from saprophytic ...

Journal of Lipid Research Volume 52, 2011 245 Copyright © 2011 by the American Society for Biochemistry and Molecular Biology, Inc. Essential fatty acids, i.e., linoleic (C18:2n-6) and -linolenic acid (C18:3n-3), which are prerequisites for normal growth, development, and function in mammals, cannot be synthesized de novo and, as such, have to be derived from diet ( 1 ). Subsequently, the C18:2...

Since Brazil is a major producer, consumer and exporter of asbestos, monitoring the occurrence of asbestos-related diseases is crucial. Whereas other asbestos-related cancers are multifactorial in origin, the major risk factor for mesothelioma is asbestos. In many countries, the occurrence of this malignancy in the population reflects the use of asbestos in the economy. In Brazil, nevertheless,...

Dear Editor, DNA methylation is one of the most important epigenetic marks and plays a central role in gene silencing in high eukaryotes. It is established by DNA methyltransferases (DNMTs), which are classified into three subfamilies. In contrast to DNMT1 and DNMT3, the biological function of DNMT2 remains elusive to date. DNMT2 was first identified in mouse and human and appears to be well co...