Ras proteins play crucial roles in cell growth regulation, signal transduction and proliferation. Abnormal Ras proteins caused by genetic mutations are more common in human cancers. Activation of Ras occurs by enzymatic attachment of Farnesyl moiety by Farnesyl transferase. It has been proven that Ftase is a potential anticancer protein target. In this study we perform a virtual screening using...

The production of aflatoxins B1 and B2 by Aspergillus tamarii (subgenus Circumdati section Flavi) is reported for the first time. The fungus was isolated from soil collected from a tea (Camellia sinensis) field in Miyazaki Prefecture, Japan. Three single-spore cultures, NRRL 25517, NRRL 25518, and NRRL 25519, were derived from subcultures of the original isolate 19 (MZ2). Each of these single-s...

O objetivo deste estudo foi comparar metodologias de extração sequencial e digestão úmida na quantificação dos níveis Cu, Zn, Fe Mn em chás Camellia sinensis. Os resultados estatísticos mostram que o método mais sensível elementos, com teores Cu faixa 13.65 a 28.73 mg kg-1, Zn entre 18.89 54.20 239.0 1403.24 kg-1 857.25 1402.98 kg-1. Na Análise Componentes Principais (PCA), aparecem relacionado...

Periodontitis adalah peradangan pada jaringan pendukung gigi yang disebabkan oleh kelompokmikroorganisme tertentu salah satunya bakteri Aggregatibacter actinomycetemcomitans, yangmenyebabkan kerusakan ligamen periodontal dan tulang alveolar. Penelitian ini bertujuan untukmembuktikan apakah ekstrak teh putih efektif menghambat pembentukan biofilm bakteriAggregatibacter actinomycetemcomitans seca...

Introduction: In this study, the effects of black tea extract of Iranian tea plant (Camellia sinensis var sinensis) and its polyphenolic pigment thearubigins were investigated on mice intestinal transit time. Method: Thearubigins were isolated by liquid-liquid fraction method. The effects of black tea extract and isolated thearubigins on intestinal propulsion were measured by charcoal propulsio...