The purpose of this study was to investigate whether the expression of cellular adhesion molecules (CAMs) is enhanced in individuals with low HDL cholesterol (HDL-C). Plasma levels of soluble vascular cell adhesion molecule-1 (sVCAM-1), intercellular adhesion molecule-1 (sICAM-1), and E-selectin (sE-selectin) were measured in subjects with low (below the 10th percentile for the Italian populati...

BACKGROUND Abdominal aortic aneurysm (AAA) is a relatively common disease in elderly. Currently, only surgical treatment has been available for ruptured AAA. Thus, it is impressing to elucidate the molecular cellular mechanisms of AAA in order to develop the effective medications. AIM This study is to explore the significant pathways and crosstalk between them in response to AAA. METHODS Th...

As obligate intracellular parasites, viruses must traverse the host-cell plasma membrane to initiate infection. This presents a formidable barrier, which they have evolved diverse strategies to overcome. Common to all entry pathways, however, is a mechanism of specific attachment to cell-surface macromolecules or 'receptors'. Receptor usage frequently defines viral tropism, and consequently, th...

One of the aspects of the reengineering problem of legacy Information Management Systems for complex Technological Process, related with working out of new program components, destined for storing and processing the retrospective information concerning the functioning of Technological Process, was considered. As an object for re-engineering processing the Computer-Aided Information System (CAMS...

Abstract Using manually collected data on the number and category of critical audit matters (CAMs) in period 2016–2017, we investigate hitherto unexplored questions whether CAMs affect firm-specific crash risk, how influence risk Chinese capital market, recognize that contain incremental information. Our findings are as follows: (1) Crash decreases after implementing new standard requiring disc...

BACKGROUND Complementary and Alternative Medicines (CAMs) are increasingly practiced in the general population; it is estimated that over 30% of patients with chronic diseases use CAMs on a regular basis. CAMs are also used in hospital settings, suggesting a growing interest in individualized therapies. One potential field of interest is pain, frequently reported by dialysis patients, and seldo...

Cell adhesion molecules (CAMs) sense the extracellular microenvironment and transmit signals to the intracellular compartment. In this investigation, we addressed the mechanism of signal generation by ectodomains of single-pass transmembrane homophilic CAMs. We analyzed the structure and homophilic interactions of carcinoembryonic antigen (CEA)-related CAM 1 (CEACAM1), which regulates cell prol...

L. japonicus, a model plant of legumes plants, is widely used in symbiotic nitrogen fixation. A large number of studies on it have been published based on the genetic, biochemical, structural studies. These results are secondhand reports that CaM is a key regulator during Rhizobial infection. In plants, there are multiple CaM genes encoding several CaM isoforms with only minor amino acid differ...