BACKGROUND There is current interest in understanding the molecular mechanisms of tumor-induced bone pain. Accumulated evidence shows that endogenous formaldehyde concentrations are elevated in the blood or urine of patients with breast, prostate or bladder cancer. These cancers are frequently associated with cancer pain especially after bone metastasis. It is well known that transient receptor...

The global burden of cancer pain is enormous and opioids, despite their side effects, remain the primary therapeutic approach. The cause of cancer pain is unknown. Mechanisms driving cancer pain differ from those mechanisms responsible for inflammatory and neuropathic pain. The prevailing hypothesis put forward to explain cancer pain posits that cancers generate and secrete mediators which sens...

Cancer and its treatment exert a heavy psychological and physical toll. Of the myriad symptoms which result, pain is common, encountered in between 30% and 60% of cancer survivors. Pain in cancer survivors is a major and growing problem, impeding the recovery and rehabilitation of patients who have beaten cancer and negatively impacting on cancer patients' quality of life, work prospects and me...

PURPOSE/OBJECTIVES To describe the meaning of cancer pain and attitudes in dealing with cancer pain among a group of African Americans with cancer. RESEARCH APPROACH Qualitative descriptive design. SETTING Three outpatient medical oncology clinics in the mid-Atlantic region. PARTICIPANTS Purposive sample of 35 self-identified African Americans older than age 18 and diagnosed with solid tu...

The Effect of Eye Movement Desensitization and Reprocessing on Pain Intensity in Cancer Patients (24-Month Follow-Up)

Barriers to cancer pain management can contribute to the undertreatment of cancer pain. No studies have documented barriers to cancer pain management in Chinese American patients. The purposes of this study in a community sample of Chinese Americans were to: describe their perceived barriers to cancer pain management; examine the relationships between these barriers and patients' ratings of pai...

BACKGROUND Cancer pain is a devastating condition. Pain in the orofacial region, may be present as the single symptom of cancer or as a symptom of cancer in its later stages. This manuscript revises in a comprehensive manner the content of the conference entitled "Orofacial Pain and Cancer" (Dolor Orofacial y Cancer) given at the VI Simposio International "Advances in Oral Cancer" on the 22 Jul...

Pain control is vital to the quality of life of patients with cancer. From pain assessment and pharmacologic management to interventional management, special features of cancer pain are outlined in this article. Many evidence-based national and societal guidelines were developed during the past decade on cancer pain management. Proper and adequate management of cancer pain is strongly recommend...

Advances in medical knowledge and treatment have resulted in improved five-year survival rates for some forms of cancer. However, pain syndromes resulting from chemotherapy, radiotherapy, surgery or interventional procedures continue to have a significant effect on cancer survivors' quality of life. Nurses are uniquely placed to assess pain in cancer survivors and ensure pain management strateg...

Terminal cancer pain remains one of the most distressing aspects pediatric oncology practice. Opioids are cornerstone management at end-of-life and fortunately, can be managed successfully. This article presents a practical step-by-step approach to alleviating terminal pain, which delivered across settings.