This meta-analysis aimed to provide an up-to-date comprehensive evaluation on the association between the MDM2 40bp indel polymorphism and cancer susceptibility. Eligible studies were retrieved by searching Web of Science, PubMed, Scopus, and Google scholar databases up to August 27, 2018. The pooled odds ratios (ORs) with 95% confidence intervals (CIs) were calculated to estimate the ...

introduction accurate estimation of the skin-absorbed dose in external radiation therapy is essential to estimating the probability of secondary carcinogenesis induction materials and methods electron contamination in prostate radiotherapy was investigated using the monte carlo (mc) code calculation. in addition, field size dependence of the skin dose was assessed. excess cancer risk induced by...

Background: The average age of women with breast cancer in Iran is at least 10 years lower in comparison to developed countries and the incidence of the disease in Iranian women is on a rise. According to studies, diets that are diverse in food groups can play a role in protecting against chronic diseases including cardiovascular diseases and cancer. Diet diversity score is an indicator used to...

aim : the present study aimed to evaluate the prevalence of positive family history of these cancers in a large population-based sample of tehran province, capital of iran. background : upper gastrointestinal (ugi) cancers (gastric and esophagus cancer) constitute a major health problem worldwide. a family history of cancer can increase the risk for developing cancer and recognized as one of th...

second to the cardiovascular disease, cancer is the main cause of death in iran. in this study some of the risk factors of breast cancer; especially the ones related to breastfeeding have been assessed. the study was a retrospective study of 100 women with breast cancer. the most important risk factors in breast cancer were number of children, age of mother on the first pregnancy. the result sh...

Background: Breast cancer is one of the most common cancers among women worldwide. Tumor protein 53 (TP53) and its regulator the mouse double murine 2 (MDM2) have important roles in tumorigenesis by playing key roles in cell division and response to DNA damage. MDM2 SNP309 T>G (rs2279744) polymorphism in the promoter region of MDM2 gene can cause dysfunction and inactivation of TP53 which promo...

background: in some verses in holy quran; 233 surat al-baghare , 15 al-ahghaf , 14 loghman and 6 al-talagh, breastfeeding, gravidity, and parity recommended to the parents and expected their children to be accountable to the parents; particularly to mothers due to tolerate of pregnancy and breastfeeding duration. methods: the case-control study included 376 patients diagnosed between      2001-...